Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADW18193.1Phosphocarrier, HPr family; InterPro IPR005698: IPR000032; KEGG: rba:RB8588 phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: Phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family. (89 aa)    
Predicted Functional Partners:
ADW18192.1
COGs: COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component); InterPro IPR006318: IPR000121: IPR008731: IPR008279; KEGG: pca:Pcar_1929 PEP-protein phosphotransferase system enzyme I; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; SPTR: Phosphoenolpyruvate--protein phosphotransferase; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase.
 
 0.999
ADW18189.1
COGs: COG2453 protein-tyrosine phosphatase; InterPro IPR016130: IPR000387: IPR000340: IPR020422; KEGG: dat:HRM2_16250 putative protein phosphatase; PFAM: Dual specificity protein phosphatase; SMART: Dual specificity phosphatase, subgroup, catalytic domain; SPTR: Putative uncharacterized protein; PFAM: Dual specificity phosphatase, catalytic domain.
 
     0.826
ADW18190.1
COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192: IPR008279; KEGG: dat:HRM2_16260 PpsA4; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; SPTR: Pyruvate phosphate dikinase PEP/pyruvate-binding; PFAM: PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain.
  
  
 0.812
ADW18187.1
InterPro IPR005358; KEGG: tai:Taci_1142 protein of unknown function UPF0153; PFAM: protein of unknown function UPF0153; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0153).
       0.773
ADW18188.1
Putative two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR020441: IPR002078: IPR001789: IPR003593; KEGG: dat:HRM2_12070 sigma-54 dependent DNA-binding response regulator (fis family protein); PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; SMART: response regulator receiver; AAA ATPase; SPTR: Helix-turn-helix, Fis-type; PFAM: Response regulator receiver domain; Sigma-54 interaction domain.
       0.773
ADW18191.1
COGs: COG0611 Thiamine monophosphate kinase; InterPro IPR006283: IPR000728: IPR010918; KEGG: dak:DaAHT2_1499 thiamine-monophosphate kinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; PRIAM: Thiamine-phosphate kinase; SPTR: Thiamine-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: thiamine-monophosphate kinase.
       0.773
ADW18194.1
KEGG: dps:DP2269 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
    0.738
rpsL
SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
    0.711
ADW16690.1
Putative PTS IIA-like nitrogen-regulatory protein PtsN; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: pca:Pcar_1936 phosphotransferase system enzyme IIA, regulates nitrogen metabolism; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: Phosphotransferase system enzyme IIA, regulates nitrogen metabolism; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
  
 0.641
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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