Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW18224.1Hypothetical protein; InterPro IPR001120: IPR012902; KEGG: dar:Daro_3039 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain. (137 aa)    
Predicted Functional Partners:
ADW18223.1
Hypothetical protein; InterPro IPR001120: IPR012902; KEGG: sfu:Sfum_2553 type II secretory pathway component PulJ-like; SPTR: Type II secretory pathway component PulJ-like; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
  
 
 0.951
ADW16836.1
COGs: COG3156 Type II secretory pathway component PulK; KEGG: dal:Dalk_5152 type II secretory pathway component PulK-like protein; SPTR: Type II secretory pathway component PulK-like protein; PFAM: General secretion pathway protein K.
  
 
 0.778
ADW18222.1
KEGG: dal:Dalk_4403 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.768
ADW16843.1
General secretion pathway protein F; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076: IPR003004: IPR011850: IPR001992; KEGG: dol:Dole_1045 general secretion pathway protein F; PFAM: Type II secretion system F domain; SPTR: General secretion pathway protein F; TIGRFAM: general secretion pathway protein F; PFAM: Bacterial type II secretion system protein F domain; TIGRFAM: general secretion pathway protein F.
  
  
 0.752
ADW18341.1
Type II secretion system F domain protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR003004: IPR018076; KEGG: dps:DP2782 type 4 fimbrial assembly protein (PilC); PFAM: Type II secretion system F domain; SPTR: Probable type 4 fimbrial assembly protein (PilC); PFAM: Bacterial type II secretion system protein F domain.
  
  
 0.752
ADW18225.1
KEGG: sce:YKL020C ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Mga2p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting.
       0.709
ADW18226.1
Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR020441: IPR002078: IPR001789: IPR002197: IPR 003593; KEGG: dol:Dole_1777 two component, sigma54 specific, Fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response reg [...]
       0.709
ADW18219.1
COGs: COG4970 Tfp pilus assembly protein FimT; InterPro IPR001120: IPR012902; KEGG: dol:Dole_0486 pilin assembly protein; SPTR: Pilin assembly protein; PFAM: Prokaryotic N-terminal methylation motif; Type II transport protein GspH; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
  
  
 0.700
ADW18470.1
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477: IPR004797; KEGG: dps:DP1704 ComE operon protein 3; PFAM: ComEC/Rec2-related protein; SPTR: Related to ComE operon protein 3; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
  
  
 0.639
pilB
Cyclic nucleotide-binding protein; COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterProIPR000595: IPR007831: IPR001482: IPR003593: IPR 013374; KEGG: dps:DP2226 type IV pilus assembly protein (TapB); PFAM: type II secretion system protein E; General secretory system II protein E domain protein; cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; AAA ATPase; SPTR: Probable type IV pilus assembly protein (TapB); TIGRFAM: type IV-A pilus assembly ATPase PilB; PFAM: GSPII_E N-terminal domain; Type II/IV secretion system protein; Cycli [...]
  
 
 0.630
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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