STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18226.1Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR020441: IPR002078: IPR001789: IPR002197: IPR 003593; KEGG: dol:Dole_1777 two component, sigma54 specific, Fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response reg [...] (465 aa)    
Predicted Functional Partners:
ADW18225.1
KEGG: sce:YKL020C ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Mga2p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting.
       0.773
ADW18227.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR003660: IPR003661: IPR 003594; KEGG: dol:Dole_1776 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
   0.762
ADW16691.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: dps:DP0442 RNA polymerase sigma-54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: Probable RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
   
 0.751
ADW16797.1
PAS sensor protein; InterPro IPR013767: IPR000014; KEGG: met:M446_4819 putative PAS/PAC sensor protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box.
 
  
   0.719
ADW18223.1
Hypothetical protein; InterPro IPR001120: IPR012902; KEGG: sfu:Sfum_2553 type II secretory pathway component PulJ-like; SPTR: Type II secretory pathway component PulJ-like; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
       0.709
ADW18224.1
Hypothetical protein; InterPro IPR001120: IPR012902; KEGG: dar:Daro_3039 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
       0.709
ADW18222.1
KEGG: dal:Dalk_4403 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.704
ADW18221.1
Na-Ca exchanger/integrin-beta4; COGs: COG3419 Tfp pilus assembly protein tip-associated adhesin PilY1; InterPro IPR018247: IPR000209: IPR003644; KEGG: dal:Dalk_4404 Tfp pilus assembly protein tip-associated adhesin PilY1-like protein; PFAM: Na-Ca exchanger/integrin-beta4; SMART: Na-Ca exchanger/integrin-beta4; SPTR: Type 4 fimbrial biogenesis protein PilY1; PFAM: Protein metal binding site; Calx-beta domain.
       0.535
ADW18219.1
COGs: COG4970 Tfp pilus assembly protein FimT; InterPro IPR001120: IPR012902; KEGG: dol:Dole_0486 pilin assembly protein; SPTR: Pilin assembly protein; PFAM: Prokaryotic N-terminal methylation motif; Type II transport protein GspH; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
       0.482
ADW18220.1
Hypothetical protein; KEGG: nvi:100117681 similar to RE11240p; SPTR: Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
       0.482
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.