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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
ADW18239.1thiamineS protein; InterPro IPR003749; KEGG: dps:DP2477 molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; SPTR: Similar to molybdopterin converting factor, subunit 1; PFAM: ThiS family. (74 aa)    
Predicted Functional Partners:
ADW18940.1
Molybdopterin biosynthesis MoaE protein; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: dps:DP2875 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Similar to molybdenum cofactor biosynthesis protein; PFAM: MoaE protein.
  
 
 0.988
ADW18242.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR006140: IPR000594; KEGG: gur:Gura_1193 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; ThiF family.
 
 0.987
ADW18121.1
GTP cyclohydrolase subunit MoaC; COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: dps:DP1483 molybdenum cofactor biosynthesis protein C (MoaC); PFAM: molybdopterin cofactor biosynthesis protein MoaC; SPTR: Probable molybdenum cofactor biosynthesis protein C (MoaC); TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC.
  
  
 0.941
ADW17210.1
Rhodanese domain protein; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: dba:Dbac_1785 rhodanese domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Rhodanese domain protein; PFAM: Rubrerythrin; Rhodanese-like domain.
    
 0.916
ADW18238.1
COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983: IPR001203; KEGG: dps:DP2476 tungsten-containing aldehyde ferredoxin oxidoreductase (AOR); PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: Related to tungsten-containing aldehyde ferredoxin oxidoreductase (AOR); PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3.
 
     0.899
ADW18075.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594; KEGG: cth:Cthe_0600 thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: Thiamine biosynthesis protein ThiF; PFAM: ThiF family; TIGRFAM: thiamine biosynthesis protein ThiF, family 2.
  
 
 0.799
ADW17156.1
COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterProIPR006638: IPR007197: IPR010505: IPR000385: IPR 013483; KEGG: dps:DP2172 molybdenum cofactor biosynthesis protein A (MoaA); PFAM: molybdenum cofactor synthesis domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Probable molybdenum cofactor biosynthesis protein A (MoaA); TIGRFAM: molybdenum cofactor biosynthesis protein A; PFAM: Molybdenum Cofactor Synthesis C; Radical SAM superfamily; TIGRFAM: molybdenum cofactor biosynthesis protein A, bacterial.
  
  
 0.779
ADW19190.1
InterPro IPR003731; KEGG: dsa:Desal_0442 dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; SPTR: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: Dinitrogenase iron-molybdenum cofactor.
  
  
 0.779
ADW18463.1
COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453: IPR008284: IPR020817; KEGG: dak:DaAHT2_1080 molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor synthesis domain protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.
  
  
 0.772
ADW19311.1
Cysteine synthase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR001926: IPR015803: IPR015273: IPR005856: IPR 002308: IPR001216; KEGG: dal:Dalk_3820 cysteine synthase; PFAM: Cysteinyl-tRNA synthetase class Ia; Pyridoxal-5'-phosphate-dependent protein beta subunit; Cysteinyl-tRNA synthetase class Ia DALR; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase; cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthases; cysteinyl-tRNA synthetase; cysteine synthase B.
  
 
 0.746
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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