Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ADW18263.1ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR001757: IPR000695: IPR018303: IPR004014: IPR 008250: IPR005834: IPR006068; KEGG: pca:Pcar_2279 cation transport ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Cation transport ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; haloacid dehalogenase-like hydrolase; Cation transporter/ATPa [...] (895 aa)    
Predicted Functional Partners:
ADW18262.1
UspA domain-containing protein; InterPro IPR006016; KEGG: pca:Pcar_2280 universal stress protein UspA-like protein; PFAM: UspA domain-containing protein; SPTR: Universal stress protein UspA-like protein; PFAM: Universal stress protein family.
  
  
 0.808
ADW17205.1
Hypothetical protein; KEGG: tga:TGAM_0557 dinitrogenase iron-molybdenum cofactor, NIF B/Y/X related; SPTR: Dinitrogenase iron-molybdenum cofactor, NIF B/Y/X related; PFAM: Protein of unknown function (DUF1104).
   
 
 0.754
ADW16976.1
COGs: COG0096 Ribosomal protein S8; InterPro IPR000630; KEGG: lga:LGAS_0304 30S ribosomal protein S8; PFAM: ribosomal protein S8; SPTR: Ribosomal protein S8; manually curated; PFAM: Ribosomal protein S8.
    
   0.642
ADW18043.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterProIPR020845: IPR009081: IPR006163: IPR000873: IPR 002123; KEGG: ppr:PBPRB0014 acyltransferase family protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: Hypothetical acyltransferase family protein; PFAM: Phosphopantetheine attachment site; Acyltransferase; AMP-binding enzyme; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.
  
 0.619
rpsM
SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
   
   0.613
ADW16609.1
FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterProIPR000253: IPR003439: IPR013525: IPR017871: IPR 003593; KEGG: cag:Cagg_0751 FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; PFAM: ABC transporter related; Forkhead-associated protein; ABC-2 type transporter; SMART: Forkhead-associated protein; AAA ATPase; SPTR: FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; PFAM: ABC transporter; FHA domain; ABC-2 type transporter.
  
 0.602
rpsE
SSU ribosomal protein S5P; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
    
   0.581
ADW18264.1
CoA-binding domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR011761: IPR000182: IPR003781; KEGG: dat:HRM2_37830 SucC4; PFAM: CoA-binding domain protein; GCN5-related N-acetyltransferase; SPTR: SucC4; PFAM: CoA binding domain; Acetyltransferase (GNAT) family; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain.
       0.578
ADW18688.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR002123: IPR020845: IPR000873; KEGG: dar:Daro_0402 AMP-dependent synthetase and ligase:phospholipid/glycerol acyltransferase; PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: AMP-dependent synthetase and ligase:Phospholipid/glycerol acyltransferase; PFAM: Acyltransferase; AMP-binding enzyme; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.
  
 0.549
ADW16966.1
COGs: COG0088 Ribosomal protein L4; InterPro IPR002136; KEGG: dak:DaAHT2_1451 ribosomal protein L4/L1e; PFAM: ribosomal protein L4/L1e; SPTR: 50S ribosomal protein L4; PFAM: Ribosomal protein L4/L1 family.
    
   0.529
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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