STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18280.1Signal peptidase I; InterPro IPR000223: IPR019759; KEGG: dol:Dole_0321 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type. (177 aa)    
Predicted Functional Partners:
ADW19285.1
COGs: COG0681 Signal peptidase I; InterPro IPR019759: IPR000223: IPR019756: IPR019757; KEGG: dps:DP0107 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Related to signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type.
  
  
 
0.923
ADW18279.1
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: dba:Dbac_0778 histone deacetylase superfamily; PFAM: histone deacetylase superfamily; SPTR: Histone deacetylase superfamily; PFAM: Histone deacetylase domain.
  
    0.776
ADW18281.1
Hypothetical protein; InterPro IPR022272; KEGG: caa:Caka_1101 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
ADW18525.1
RNase HII; COGs: COG0164 Ribonuclease HII; InterPro IPR001352; KEGG: dps:DP2806 ribonuclease HII; PFAM: ribonuclease HII/HIII; PRIAM: Ribonuclease H; SPTR: Ribonuclease HII; PFAM: Ribonuclease HII.
 
    0.761
ADW18973.1
COGs: COG0851 Septum formation topological specificity factor; InterPro IPR005527; KEGG: maq:Maqu_2337 cell division topological specificity factor MinE; PFAM: Septum formation topological specificity factor MinE; SPTR: Cell division topological specificity factor; TIGRFAM: cell division topological specificity factor MinE; PFAM: Septum formation topological specificity factor MinE; TIGRFAM: cell division topological specificity factor MinE.
   
    0.751
ADW19097.1
SSU ribosomal protein S12P methylthiotransferase; COGs: COG0621 2-methylthioadenine synthetase; InterProIPR002792: IPR013848: IPR007197: IPR005840: IPR 020612: IPR006638: IPR005839; KEGG: dak:DaAHT2_2543 MiaB-like tRNA modifying enzyme YliG; PFAM: protein of unknown function UPF0004; Radical SAM domain protein; deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; TIGRFAM: MiaB-like tRNA modifying enzyme YliG; RNA modification enzyme, MiaB family; PFAM: TRAM domain; Radical SAM superfamily; Uncharacterized protein family [...]
  
    0.750
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.718
ADW19084.1
COGs: COG0342 Preprotein translocase subunit SecD; InterPro IPR003335: IPR005791: IPR005665; KEGG: dps:DP0806 protein-export membrane protein SecD; PFAM: SecD/SecF/SecDF export membrane protein; SPTR: Related to protein-export membrane protein SecD; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF; PFAM: Protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF.
  
  
 0.656
ADW18278.1
Hydantoinase/oxoprolinase; COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040: IPR002821; KEGG: dba:Dbac_0779 hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; SPTR: Hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region.
       0.615
ADW16997.1
Site-2 protease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR008915: IPR001478: IPR004387; KEGG: dak:DaAHT2_0974 membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Membrane-associated zinc metalloprotease; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP.
 
  
 0.601
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.