STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18284.1Metallophosphoesterase; InterPro IPR004843; KEGG: afn:Acfer_2068 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Ser/Thr protein phosphatase family protein; PFAM: Calcineurin-like phosphoesterase. (326 aa)    
Predicted Functional Partners:
ADW16898.1
Adenylate/guanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789: IPR001054: IPR018297; KEGG: bja:blr2288 two-component hybrid sensor and regulator; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; SPTR: Adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain.
    
 0.920
ADW18966.1
Adenylate/guanylate cyclase with GAF sensor(s); COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054: IPR003018; KEGG: dal:Dalk_4220 adenylate/guanylate cyclase with GAF sensor(s); PFAM: GAF domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: GAF domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase with GAF sensor(S); manually curated; PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain.
     
 0.918
ADW17354.1
5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR006179: IPR004843: IPR008334: IPR006146; KEGG: psa:PST_4140 5'-nucleotidase; PFAM: 5'-Nucleotidase domain-containing protein; metallophosphoesterase; SPTR: 5'-nucleotidase; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain.
   
 
 0.913
ADW19286.1
COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843: IPR008334: IPR006179: IPR006146; KEGG: aci:ACIAD0015 putative 5'-nucleotidase NucA precursor; PFAM: 5'-Nucleotidase domain-containing protein; metallophosphoesterase; PRIAM: 5'-nucleotidase; SPTR: NAD nucleotidase; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; TIGRFAM: NAD pyrophosphatase/5'-nucleotidase NadN.
   
 
 0.913
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.905
ADW16754.1
HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR006402: IPR006439: IPR005834; KEGG: dak:DaAHT2_2004 HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid d [...]
    
  0.903
ADW18180.1
Conserved hypothetical protein CHP00730; COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005269; KEGG: cja:CJA_1346 decarboxylase family protein; PFAM: Conserved hypothetical protein CHP00730; SPTR: Decarboxylase family protein; PFAM: Domain of unknown function (DUF3412); Possible lysine decarboxylase.
    
  0.902
ADW17930.1
COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769: IPR000362: IPR019468: IPR020557; KEGG: dak:DaAHT2_0801 adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; SPTR: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
  0.900
ADW18084.1
Adenylate cyclase; COGs: COG2954 conserved hypothetical protein; InterPro IPR008172: IPR012042; KEGG: dds:Ddes_1849 adenylate cyclase; PFAM: adenylate cyclase; SPTR: Adenylate cyclase; PFAM: CYTH domain.
     
  0.900
ADW18846.1
5'-nucleotidase; COGs: COG0496 acid phosphatase; InterPro IPR002828; KEGG: dak:DaAHT2_2449 stationary-phase survival protein SurE; PFAM: Survival protein SurE; SPTR: Stationary-phase survival protein SurE; TIGRFAM: stationary-phase survival protein SurE; PFAM: Survival protein SurE; TIGRFAM: 5'/3'-nucleotidase SurE.
     
  0.900
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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