STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADW18296.1Cyclase family protein; COGs: COG1878 metal-dependent hydrolase; InterPro IPR007325; KEGG: aac:Aaci_2550 cyclase family protein; PFAM: cyclase family protein; SPTR: Cyclase family protein; PFAM: Putative cyclase. (208 aa)    
Predicted Functional Partners:
ADW18297.1
COGs: COG0364 Glucose-6-phosphate 1-dehydrogenase; InterPro IPR001282: IPR019796; KEGG: mta:Moth_2302 glucose-6-phosphate 1-dehydrogenase; PFAM: glucose-6-phosphate dehydrogenase; PRIAM: Glucose-6-phosphate dehydrogenase; SPTR: Glucose-6-phosphate 1-dehydrogenase; PFAM: Glucose-6-phosphate dehydrogenase, C-terminal domain; Glucose-6-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glucose-6-phosphate 1-dehydrogenase.
 
     0.930
ADW18298.1
COGs: COG1023 6-phosphogluconate dehydrogenase; InterPro IPR006183: IPR006115: IPR006114: IPR004849; KEGG: cte:CT1874 6-phosphogluconate dehydrogenase-like protein; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain-containing protein; SPTR: 6-phosphogluconate dehydrogenase, decarboxylating; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase, C-terminal domain; NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 6-phosphogluconate dehydrogenase (decarboxylating); 6-phosphogluconate deh [...]
 
     0.921
ADW16802.1
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR006311: IPR017900: IPR017909: IPR017896; KEGG: geo:Geob_1593 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
     
  0.900
ADW18049.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017900: IPR017896: IPR014603; KEGG: drm:Dred_0462 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
     
  0.900
ADW19350.1
COGs: COG0788 Formyltetrahydrofolate hydrolase; InterPro IPR002912: IPR002376: IPR004810; KEGG: bvu:BVU_3850 formyltetrahydrofolate deformylase; PFAM: formyl transferase domain protein; amino acid-binding ACT domain protein; SPTR: Formyltetrahydrofolate deformylase; TIGRFAM: formyltetrahydrofolate deformylase; PFAM: Formyl transferase; TIGRFAM: formyltetrahydrofolate deformylase.
     
  0.900
ADW18501.1
COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000089: IPR000891: IPR003379: IPR001882; KEGG: dal:Dalk_3782 conserved carboxylase region; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; SPTR: Conserved carboxylase region; PFAM: HMGL-like; Conserved carboxylase domain; Biotin-requiring enzyme.
    
  0.814
ADW19382.1
COGs: COG1274 Phosphoenolpyruvate carboxykinase (GTP); InterPro IPR008209; KEGG: dps:DP1093 phosphoenolpyruvate carboxykinase; PFAM: phosphoenolpyruvate carboxykinase (GTP); PRIAM: Phosphoenolpyruvate carboxykinase (GTP); SPTR: Probable phosphoenolpyruvate carboxykinase; PFAM: Phosphoenolpyruvate carboxykinase.
     
 0.808
ADW16573.1
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.805
ADW16228.1
Fumarase; COGs: COG0114 Fumarase; InterProIPR020557: IPR000362: IPR003031: IPR005677: IPR 018951; KEGG: dap:Dacet_2357 fumarate hydratase, class II; PFAM: fumarate lyase; Fumarase C-like; SPTR: Fumarate hydratase, class II; TIGRFAM: fumarate hydratase, class II; PFAM: Lyase; Fumarase C C-terminus; TIGRFAM: fumarate hydratase, class II.
     
  0.800
ADW17373.1
COGs: COG2225 Malate synthase; InterPro IPR011076; KEGG: sti:Sthe_2906 malate synthase A; PFAM: Malate synthase family protein; PRIAM: Malate synthase; SPTR: Malate synthase; PFAM: Malate synthase; TIGRFAM: malate synthase A.
     
  0.800
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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