STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18327.1COGs: COG1189 rRNA methylase; InterPro IPR002942: IPR002877: IPR004538; KEGG: dak:DaAHT2_0442 hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; SPTR: Hemolysin A; TIGRFAM: hemolysin A; manually curated; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein. (269 aa)    
Predicted Functional Partners:
ADW18328.1
Tol-pal system protein YbgF; COGs: COG1729 conserved hypothetical protein; InterPro IPR019734: IPR013026: IPR001440: IPR014162; KEGG: dak:DaAHT2_0890 tol-pal system protein YbgF; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: TPR repeat; TIGRFAM: tol-pal system protein YbgF; PFAM: Tetratricopeptide repeat; TIGRFAM: tol-pal system protein YbgF.
       0.780
ADW18326.1
SH3 type 3 domain protein; COGs: COG3807 conserved hypothetical protein; InterPro IPR003646: IPR013247: IPR010466; KEGG: dak:DaAHT2_2324 protein of unknown function DUF1058; PFAM: SH3 type 3 domain protein; protein of unknown function DUF1058; SMART: SH3 domain protein; SPTR: Putative uncharacterized protein; PFAM: Bacterial SH3 domain.
       0.773
ADW19027.1
Histidine triad (HIT) protein; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310: IPR019808; KEGG: dak:DaAHT2_1965 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: Histidine triad (HIT) protein; PFAM: HIT domain.
      0.702
ADW17739.1
COGs: COG0061 sugar kinase; InterPro IPR002504; KEGG: dak:DaAHT2_1073 NAD(+) kinase; PFAM: ATP-NAD/AcoX kinase; SPTR: NAD(+) kinase; PFAM: ATP-NAD kinase.
  
  
 0.622
ADW18547.1
COGs: COG1154 Deoxyxylulose-5-phosphate synthase; InterPro IPR005477: IPR005475: IPR005476: IPR020826; KEGG: dps:DP2700 1-deoxy-D-xylulose-5-phosphate synthase; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: 1-deoxy-D-xylulose-5-phosphate synthase; TIGRFAM: deoxyxylulose-5-phosphate synthase; PFAM: Transketolase, C-terminal domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Transketolase, pyrimidine binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase.
  
    0.565
ADW18329.1
TolB domain-containing protein; COGs: COG0823 Periplasmic component of the Tol biopolymer transport system; InterPro IPR014167: IPR007195: IPR011659; KEGG: dps:DP2412 TolB protein [precursor]; PFAM: TolB domain-containing protein; WD40-like beta Propeller containing protein; SPTR: Protein tolB; PFAM: WD40-like Beta Propeller Repeat; TolB amino-terminal domain; TIGRFAM: tol-pal system beta propeller repeat protein TolB.
       0.561
ffh
Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...]
  
    0.463
ADW18548.1
COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: dps:DP2699 geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; SPTR: Probable geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase.
 
    0.461
ADW18330.1
KEGG: dma:DMR_13910 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: TolA protein; TonB family C-terminal domain.
     
 0.452
ADW16500.1
COGs: COG0143 Methionyl-tRNA synthetase; InterProIPR002547: IPR014758: IPR002304: IPR004495: IPR 015413; KEGG: dps:DP0786 methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); t-RNA-binding domain-containing protein; SPTR: Probable methionyl-tRNA synthetase; TIGRFAM: methionyl-tRNA synthetase; methionyl-tRNA synthetase, beta subunit; PFAM: Anticodon-binding domain; tRNA synthetases class I (M); Putative tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; methionyl-tRNA synthetase.
 
    0.441
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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