Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW18338.1Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608: IPR011078; KEGG: dps:DP2780 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: Putative uncharacterized protein; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. (235 aa)    
Predicted Functional Partners:
ADW18337.1
Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR001130: IPR018228: IPR012278: IPR015991; KEGG: dps:DP2779 hypothetical protein; PFAM: TatD-related deoxyribonuclease; SPTR: Putative uncharacterized protein; TIGRFAM: hydrolase, TatD family; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family.
 
   0.861
ADW18905.1
Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: dak:DaAHT2_2303 protein of unknown function DUF152; PFAM: protein of unknown function DUF152; SPTR: Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family.
  
  
 0.851
ADW16501.1
InterPro IPR003425; KEGG: dak:DaAHT2_1889 protein of unknown function YGGT; PFAM: protein of unknown function YGGT; SPTR: Putative uncharacterized protein; PFAM: YGGT family.
 
  
 0.824
ADW17738.1
COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR000304: IPR004455; KEGG: gme:Gmet_0899 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; PRIAM: Pyrroline-5-carboxylate reductase; SPTR: Pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase.
  
 0.817
ADW18339.1
Nucleotide sugar dehydrogenase; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732: IPR014026: IPR014027: IPR017476; KEGG: dak:DaAHT2_1793 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose d [...]
       0.782
ADW16866.1
UDP-N-acetylmuramyl-tripeptide synthetase; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterProIPR000713: IPR013221: IPR004101: IPR005761: IPR 005863; KEGG: dps:DP2901 putative bifunctional UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase/UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimel [...]
  
    0.772
ADW16974.1
COGs: COG0198 Ribosomal protein L24; InterPro IPR005824: IPR003256: IPR005825; KEGG: dps:DP1135 50S ribosomal protein L24; PFAM: KOW domain protein; SMART: KOW domain protein; SPTR: 50S ribosomal protein L24; TIGRFAM: ribosomal protein L24; PFAM: KOW motif; TIGRFAM: ribosomal protein L24, bacterial/organelle.
   
    0.727
ADW17118.1
Maf protein; COGs: COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; InterPro IPR003697; KEGG: dps:DP1711 septum formation protein Maf; PFAM: Maf family protein; SPTR: Maf-like protein DP1711; TIGRFAM: maf protein; PFAM: Maf-like protein; TIGRFAM: MAF protein.
    0.721
ADW17921.1
23S rRNA m(2)A-2503 methyltransferase; COGs: COG0820 Fe-S-cluster redox enzyme; InterPro IPR004383: IPR006638: IPR007197; KEGG: dps:DP1935 hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Ribosomal RNA large subunit methyltransferase N; TIGRFAM: radical SAM enzyme, Cfr family; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM enzyme, Cfr family.
 
     0.566
nifJ
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017896: IPR017900: IPR002880: IPR 019752: IPR019456: IPR011766; KEGG: dak:DaAHT2_0906 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavod [...]
  
  
 0.510
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.