Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW18351.1Transcriptional regulator, MerR family; COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: sfu:Sfum_0360 MerR family transcriptional regulator; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: Transcriptional regulator, MerR family; PFAM: MerR family regulatory protein. (147 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.744
glnA
COGs: COG0174 Glutamine synthetase; InterPro IPR004809: IPR008147: IPR008146; KEGG: dat:HRM2_45740 GlnA2; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; PRIAM: Glutamate--ammonia ligase; SPTR: Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.
  
 
 0.725
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.720
ADW18352.1
COGs: COG5557 Polysulphide reductase; InterPro IPR005614; KEGG: glo:Glov_3346 polysulphide reductase NrfD; PFAM: Polysulphide reductase NrfD; SPTR: Polysulphide reductase NrfD; PFAM: Polysulphide reductase, NrfD.
 
     0.698
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.693
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   0.690
ADW17348.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 000700: IPR008207: IPR001610: IPR003661: IPR003594: IPR013656:I PR013767; KEGG: alv:Alvin_2605 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator re [...]
   
 
 0.526
ADW18652.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003018: IPR 003661: IPR003594: IPR001789: IPR008207: IPR005467: IPR000700:I PR013767: IPR013655: IPR013656; KEGG: alv:Alvin_0242 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain pro [...]
   
 
 0.514
ADW18515.1
Heat shock protein DnaJ domain protein; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623: IPR003095: IPR002939: IPR018253; KEGG: dps:DP1965 chaperone protein DnaJ; PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Related to chaperone protein DnaJ; PFAM: DnaJ C terminal region; DnaJ domain; TIGRFAM: chaperone protein DnaJ.
  
 
 0.498
ADW19106.1
COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623: IPR002939: IPR003095: IPR018253; KEGG: nwa:Nwat_1252 heat shock protein DnaJ domain-containing protein; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Heat shock protein DnaJ-like; PFAM: DnaJ C terminal region; DnaJ domain.
  
 
 0.498
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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