Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ADW18353.1Membrane protease FtsH catalytic subunit; COGs: COG0465 ATP-dependent Zn protease; InterProIPR003593: IPR003959: IPR000642: IPR003960: IPR 005936; KEGG: dak:DaAHT2_0902 ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase central domain protein; PRIAM: Microtubule-severing ATPase; SMART: AAA ATPase; SPTR: ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH. (643 aa)    
Predicted Functional Partners:
ADW16506.1
COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904: IPR000836; KEGG: tmt:Tmath_2015 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase.
  
  
 0.792
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
   0.768
rpsK
SSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
   
 
 0.759
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.753
ADW16848.1
COGs: COG0293 23S rRNA methylase; InterPro IPR002877: IPR016448; KEGG: dps:DP2909 ribosomal RNA methyltransferase (FtsJ); PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; SPTR: Ribosomal RNA large subunit methyltransferase E; PFAM: FtsJ-like methyltransferase; TIGRFAM: cell division protein FtsJ.
  
  
 0.749
rpsJ
SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
   0.747
ADW18185.1
COGs: COG1219 ATP-dependent protease Clp ATPase subunit; InterProIPR004487: IPR017948: IPR010603: IPR013093: IPR 019489: IPR003593; KEGG: dak:DaAHT2_1302 ATP-dependent Clp protease, ATP-binding subunit ClpX; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease, ATP-binding subunit ClpX; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit ClpX; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ClpX C4-type zinc finger; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX).
   
  
 0.747
rplQ
COGs: COG0203 Ribosomal protein L17; InterPro IPR000456; KEGG: dak:DaAHT2_1424 ribosomal protein L17; PFAM: ribosomal protein L17; SPTR: Ribosomal protein L17; TIGRFAM: ribosomal protein L17; manually curated; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17.
   
 
 0.741
ADW16976.1
COGs: COG0096 Ribosomal protein S8; InterPro IPR000630; KEGG: lga:LGAS_0304 30S ribosomal protein S8; PFAM: ribosomal protein S8; SPTR: Ribosomal protein S8; manually curated; PFAM: Ribosomal protein S8.
   
 
 0.740
ADW16956.1
COGs: COG0244 Ribosomal protein L10; InterPro IPR001790; KEGG: dps:DP1115 50S ribosomal protein L10; PFAM: ribosomal protein L10; SPTR: 50S ribosomal protein L10; PFAM: Ribosomal protein L10.
   
 
 0.733
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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