STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18356.1Sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterPro IPR002078: IPR003593: IPR020441: IPR002197; KEGG: pca:Pcar_1208 two component signal transduction response regulator; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; manually curated; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain. (361 aa)    
Predicted Functional Partners:
ADW18355.1
Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595: IPR002373: IPR018488; KEGG: dal:Dalk_3876 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain.
   
   0.805
ADW16691.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: dps:DP0442 RNA polymerase sigma-54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: Probable RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
   
 0.775
ADW16797.1
PAS sensor protein; InterPro IPR013767: IPR000014; KEGG: met:M446_4819 putative PAS/PAC sensor protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box.
 
  
   0.731
ADW18175.1
PAS sensor protein; InterProIPR000014: IPR000700: IPR003018: IPR013656: IPR 003661: IPR001610; KEGG: dat:HRM2_42110 GGDEF domain family protein; PFAM: GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: GAF domain protein; PAC repeat-containing protein; histidine kinase A domain protein; SPTR: GGDEF domain family protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.
  
 
 0.499
ADW18354.1
Nuclease (SNase domain-containing protein); COGs: COG1525 Micrococcal nuclease (thermonuclease) homologs; InterPro IPR006021; KEGG: dma:DMR_41750 putative nuclease; PFAM: nuclease (SNase domain-containing protein); SMART: nuclease (SNase domain-containing protein); SPTR: Putative nuclease; PFAM: Staphylococcal nuclease homologue.
       0.491
ADW18386.1
Flagellar biosynthesis protein (FlhG); COGs: COG0455 ATPase involved in chromosome partitioning; KEGG: dps:DP2677 flagellar biosynthesis protein (FlhG); SPTR: Cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
  
 
 0.474
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.