Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ADW18356.1Sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterPro IPR002078: IPR003593: IPR020441: IPR002197; KEGG: pca:Pcar_1208 two component signal transduction response regulator; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; manually curated; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain. (361 aa)    
Predicted Functional Partners:
ADW18355.1
Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595: IPR002373: IPR018488; KEGG: dal:Dalk_3876 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain.
   
   0.799
ADW16691.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: dps:DP0442 RNA polymerase sigma-54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: Probable RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
   
 0.781
ADW16797.1
PAS sensor protein; InterPro IPR013767: IPR000014; KEGG: met:M446_4819 putative PAS/PAC sensor protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box.
 
  
   0.722
ADW18354.1
Nuclease (SNase domain-containing protein); COGs: COG1525 Micrococcal nuclease (thermonuclease) homologs; InterPro IPR006021; KEGG: dma:DMR_41750 putative nuclease; PFAM: nuclease (SNase domain-containing protein); SMART: nuclease (SNase domain-containing protein); SPTR: Putative nuclease; PFAM: Staphylococcal nuclease homologue.
       0.491
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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