STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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[Homology]
Score
csrACarbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (81 aa)    
Predicted Functional Partners:
fliW
Protein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
 
 0.999
ADW18185.1
COGs: COG1219 ATP-dependent protease Clp ATPase subunit; InterProIPR004487: IPR017948: IPR010603: IPR013093: IPR 019489: IPR003593; KEGG: dak:DaAHT2_1302 ATP-dependent Clp protease, ATP-binding subunit ClpX; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease, ATP-binding subunit ClpX; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit ClpX; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ClpX C4-type zinc finger; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX).
   
  
 0.804
ADW18399.1
COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492: IPR013384; KEGG: pca:Pcar_1148 flagellar hook-filament junction protein; PFAM: flagellin domain protein; SPTR: Flagellin-like; TIGRFAM: flagellar hook-associated protein 3; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; TIGRFAM: flagellar hook-associated protein 3.
 
  
 0.793
ADW18398.1
COGs: COG1256 Flagellar hook-associated protein; InterPro IPR002371: IPR001444: IPR010930; KEGG: dps:DP2689 flagellar hook-associated protein 1 (FlgK); PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: Related to Flagellar hook-associated protein 1 (FlgK); TIGRFAM: flagellar hook-associated protein FlgK; PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK.
 
  
 0.791
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
  
 0.770
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
      
 0.764
ADW18163.1
3-oxoacyl-(acyl-carrier-protein) synthase III; COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); InterPro IPR004655: IPR013751: IPR013747; KEGG: dak:DaAHT2_1290 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain-containing protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase I; SPTR: 3-oxoacyl-(Acyl-carrier-protein) synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl [...]
      
 0.764
ADW18672.1
COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR004789: IPR002912: IPR019455; KEGG: dps:DP2770 acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: Probable acetolactate synthase, small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit.
      
 0.764
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
      
 0.764
ADW18312.1
Flagellar protein FliS; COGs: COG1516 Flagellin-specific chaperone FliS; InterPro IPR003713; KEGG: pca:Pcar_1111 flagellar protein FliS; PFAM: flagellar protein FliS; SPTR: Flagellar protein FliS; TIGRFAM: flagellar protein FliS; PFAM: Flagellar protein FliS; TIGRFAM: flagellar biosynthetic protein FliS.
 
  
 0.762
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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