Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW18403.1Secretion protein HlyD family protein; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: tin:Tint_1813 secretion protein HlyD family protein; PFAM: secretion protein HlyD family protein; SPTR: Putative Secretion protein HlyD; PFAM: HlyD family secretion protein. (362 aa)    
Predicted Functional Partners:
ADW17635.1
ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR000412: IPR013525; KEGG: slt:Slit_2515 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: Putative uncharacterized protein; PFAM: ABC-2 type transporter.
  
 0.922
ADW17636.1
ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR000412: IPR013525; KEGG: sfu:Sfum_2392 fis family transcriptional regulator; PFAM: ABC-2 type transporter; SPTR: Transcriptional regulator, Fis family; PFAM: ABC-2 type transporter.
  
 0.901
ADW17637.1
ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: slt:Slit_2512 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter.
  
 0.883
ADW17804.1
ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterProIPR003593: IPR003439: IPR003838: IPR017911: IPR 017871: IPR018087; KEGG: hse:Hsero_2045 antimicrobial peptide ABC transporter ATPase; PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; SPTR: Macrolide export ATP-binding/permease protein MacB; PFAM: ABC transporter; Predicted permease.
  
  
 0.819
ADW18404.1
Protein of unknown function UPF0047; COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: dsa:Desal_3330 protein of unknown function UPF0047; PFAM: protein of unknown function UPF0047; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme.
       0.773
ADW18406.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR003661: IPR 003594: IPR004358; KEGG: wsu:WS1727 sensor/response regulator hybrid; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; SPTR: SENSOR/RESPONSE REGULATOR HYBRID; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regula [...]
     
 0.693
ADW17019.1
COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: ote:Oter_1456 outer membrane efflux protein; PFAM: outer membrane efflux protein; SPTR: Outer membrane efflux protein; PFAM: Outer membrane efflux protein.
 
 
 0.688
ADW18142.1
Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: pin:Ping_3708 ABC transporter permease protein; PFAM: protein of unknown function DUF214; SPTR: ABC transporter permease protein; PFAM: Predicted permease.
 
  
 0.687
ADW18141.1
Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: slt:Slit_2078 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: Putative uncharacterized protein; PFAM: Predicted permease.
 
  
 0.680
ADW17398.1
COGs: COG1538 Outer membrane protein; InterPro IPR010131: IPR003423; KEGG: app:CAP2UW1_1523 RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; SPTR: RND efflux system, outer membrane lipoprotein, NodT family; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family.
 
 
 0.653
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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