STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADW18410.1COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR000182: IPR003702; KEGG: dps:DP0659 4-hydroxybutyrate CoA-transferase; PFAM: acetyl-CoA hydrolase/transferase; GCN5-related N-acetyltransferase; SPTR: Probable 4-hydroxybutyrate CoA-transferase; PFAM: Acetyltransferase (GNAT) family; Acetyl-CoA hydrolase/transferase N-terminal domain. (626 aa)    
Predicted Functional Partners:
ADW18411.1
CoA-binding domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterProIPR011761: IPR003781: IPR005811: IPR013650: IPR 018087; KEGG: dak:DaAHT2_1111 CoA-binding domain protein; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain.
     0.964
ADW17315.1
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterProIPR006158: IPR005129: IPR006099: IPR006159: IPR 006098; KEGG: app:CAP2UW1_0492 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; ArgK protein; cobalamin B12-binding domain protein; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: ArgK protein; Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain.
  
 
 0.915
ADW16431.1
ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR011761: IPR003781: IPR013650; KEGG: dal:Dalk_2592 CoA-binding domain protein; PFAM: ATP-grasp domain protein; CoA-binding domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain.
     0.882
ADW18062.1
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099: IPR006098: IPR006159: IPR006158; KEGG: dat:HRM2_32470 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; PRIAM: Methylmalonyl-CoA mutase; SPTR: Sbm; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain.
  
 
 0.850
ADW19218.1
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099: IPR006158: IPR006098: IPR006159; KEGG: vpr:Vpar_1762 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; PRIAM: Methylmalonyl-CoA mutase; SPTR: Putative uncharacterized protein; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain.
  
 
 0.850
ADW19219.1
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099: IPR006098; KEGG: rrs:RoseRS_0544 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase, heterodimeric type, beta chain; methylmalonyl-CoA mutase C-terminal domain.
  
 
 0.850
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
 0.793
ADW18413.1
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: dps:DP2831 hypothetical protein; PFAM: histone deacetylase superfamily; SPTR: Putative uncharacterized protein; PFAM: Histone deacetylase domain.
      0.742
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 
 0.729
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.720
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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