STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18412.1COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644; KEGG: dps:DP2830 acetoin utilization protein AcuB; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Related to acetoin utilization protein (AcuB); PFAM: CBS domain. (218 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.860
ADW18413.1
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: dps:DP2831 hypothetical protein; PFAM: histone deacetylase superfamily; SPTR: Putative uncharacterized protein; PFAM: Histone deacetylase domain.
 
    0.859
ADW18411.1
CoA-binding domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterProIPR011761: IPR003781: IPR005811: IPR013650: IPR 018087; KEGG: dak:DaAHT2_1111 CoA-binding domain protein; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain.
       0.781
ADW18410.1
COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR000182: IPR003702; KEGG: dps:DP0659 4-hydroxybutyrate CoA-transferase; PFAM: acetyl-CoA hydrolase/transferase; GCN5-related N-acetyltransferase; SPTR: Probable 4-hydroxybutyrate CoA-transferase; PFAM: Acetyltransferase (GNAT) family; Acetyl-CoA hydrolase/transferase N-terminal domain.
  
    0.669
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
     0.444
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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