Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW18431.1Sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterPro IPR002078: IPR003593: IPR020441: IPR002197; KEGG: dak:DaAHT2_1742 sigma54 specific transcriptional regulator, fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; SPTR: Sigma54 specific transcriptional regulator, Fis family; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRFAM: PAS domain S-box. (525 aa)    
Predicted Functional Partners:
ADW16691.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: dps:DP0442 RNA polymerase sigma-54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: Probable RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
   
 0.766
ADW18430.1
COGs: COG1194 A/G-specific DNA glycosylase; InterProIPR003265: IPR003651: IPR020476: IPR000086: IPR 004035: IPR020084: IPR005760; KEGG: dba:Dbac_1764 A/G-specific adenine glycosylase; PFAM: NUDIX hydrolase; HhH-GPD family protein; iron-sulfur cluster loop; SMART: HhH-GPD family protein; iron-sulfur cluster loop; SPTR: Putative uncharacterized protein; TIGRFAM: A/G-specific adenine glycosylase; PFAM: NUDIX domain; HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif; TIGRFAM: mutator mutT protein; A/G-specific adenine glycosylase.
       0.518
ADW18432.1
KEGG: hha:Hhal_0141 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.449
ADW18429.1
Hypothetical protein; InterPro IPR022265; KEGG: dat:HRM2_13290 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: hypothetical protein; TIGRFAM: conserved hypothetical protein TIGR03790.
   
   0.412
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.