STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Experiments
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[Homology]
Score
ADW18442.1Transcriptional regulator, XRE family; COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; InterPro IPR001387: IPR013096; KEGG: sfu:Sfum_4068 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family; PFAM: Cupin domain; Helix-turn-helix. (436 aa)    
Predicted Functional Partners:
ADW16934.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013655: IPR013656: IPR013767: IPR003661: IPR 003594: IPR004358: IPR000014: IPR001610: IPR005467: IPR000700; KEGG: mba:Mbar_A0404 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: PAS fold family; TI [...]
   
 
 0.914
ADW17844.1
COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterProIPR000014: IPR001610: IPR003661: IPR003594: IPR 013655: IPR013656: IPR004358: IPR005467: IPR000700; KEGG: azo:azo2457 putative sensory box histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: Multi-sensor signal transduction histidine kinas [...]
   
 
 0.914
ADW17808.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003661: IPR003594: IPR004358: IPR 005467; KEGG: pca:Pcar_0361 two component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: Two component sensor histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 
 0.907
ADW18958.1
Histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR005467: IPR003594; KEGG: dak:DaAHT2_0503 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
   
 
 0.892
ADW18652.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003018: IPR 003661: IPR003594: IPR001789: IPR008207: IPR005467: IPR000700:I PR013767: IPR013655: IPR013656; KEGG: alv:Alvin_0242 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain pro [...]
  
  
 0.806
ADW18443.1
Sulfatase; COGs: COG1368 Phosphoglycerol transferase and related protein alkaline phosphatase superfamily; InterPro IPR000917; KEGG: alv:Alvin_1043 sulfatase; PFAM: sulfatase; SPTR: Sulfatase; PFAM: Sulfatase.
       0.773
ADW18440.1
ANTAR domain protein with unknown sensor; COGs: COG3707 Response regulator with putative antiterminator output domain; InterPro IPR005561: IPR003018; KEGG: dal:Dalk_0523 ANTAR domain protein with unknown sensor; PFAM: GAF domain protein; ANTAR domain protein; SMART: GAF domain protein; SPTR: Putative uncharacterized protein; PFAM: GAF domain; ANTAR domain.
  
     0.623
ADW18880.1
KEGG: hch:HCH_04427 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2971).
  
     0.610
ADW17378.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR009594: IPR000005; KEGG: dma:DMR_01320 AraC family transcriptional regulator; PFAM: AraC-type transcriptional regulator domain protein; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-type transcriptional regulator N-terminus.
 
 
 0.530
ADW17951.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284: IPR007127: IPR009042: IPR007627: IPR 007624: IPR007630: IPR000943; KEGG: dps:DP2503 RNA polymerase sigma factor (RpoD); PFAM: sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 factor, region 1.1; Sigma-70 region 3; Sigma- [...]
  
 
 0.530
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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