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leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (564 aa)    
Predicted Functional Partners:
ADW18508.1
COGs: COG0065 3-isopropylmalate dehydratase large subunit; InterPro IPR001030: IPR018136: IPR011826: IPR006251; KEGG: dak:DaAHT2_0530 homoaconitate hydratase family protein; PFAM: aconitate hydratase domain-containing protein; SPTR: Homoaconitate hydratase family protein; TIGRFAM: homoaconitate hydratase family protein; 3-isopropylmalate dehydratase; PFAM: Aconitase family (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit; homoaconitate hydratase family protein; Belongs to the aconitase/IPM isomerase family.
 
 0.987
ADW18827.1
COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786: IPR018300: IPR001544; KEGG: dps:DP0192 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched-chain-amino-acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II.
  
 0.984
ADW18509.1
COGs: COG0066 3-isopropylmalate dehydratase small subunit; InterPro IPR000573; KEGG: dps:DP1958 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain-containing protein; SPTR: Related to 3-isopropylmalate dehydratase, small subunit; PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit.
  
 
 0.983
ilvD
COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR020558: IPR004404: IPR000581; KEGG: pdi:BDI_2073 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.956
nifJ
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017896: IPR017900: IPR002880: IPR 019752: IPR019456: IPR011766; KEGG: dak:DaAHT2_0906 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavod [...]
  
 
 0.949
ADW18672.1
COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR004789: IPR002912: IPR019455; KEGG: dps:DP2770 acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: Probable acetolactate synthase, small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit.
 
 
 0.943
ADW16623.1
COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912; KEGG: dvu:DVU0361 acetolactate synthase 1 regulatory subunit; PFAM: amino acid-binding ACT domain protein; SPTR: Amino acid-binding ACT domain protein; PFAM: ACT domain; TIGRFAM: acetolactate synthase, small subunit.
 
 
 0.934
ADW16908.1
COGs: COG0183 Acetyl-CoA acetyltransferase; InterProIPR020616: IPR020617: IPR002155: IPR020615: IPR 020610; KEGG: dol:Dole_0671 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases.
  
 
 0.934
ADW17407.1
COGs: COG0183 Acetyl-CoA acetyltransferase; InterProIPR002155: IPR020616: IPR020617: IPR020615: IPR 020610: IPR020613; KEGG: cbt:CLH_0482 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases.
  
 
 0.934
ADW17873.1
COGs: COG0183 Acetyl-CoA acetyltransferase; InterProIPR002155: IPR020616: IPR020617: IPR020615: IPR 020610: IPR020613; KEGG: dol:Dole_2187 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases.
  
 
 0.934
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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