STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18457.1COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644: IPR002550; KEGG: dps:DP2605 hypothetical protein; PFAM: CBS domain containing protein; protein of unknown function DUF21; SPTR: Putative uncharacterized protein; PFAM: CBS domain; Domain of unknown function DUF21. (344 aa)    
Predicted Functional Partners:
ADW18456.1
COGs: COG0260 Leucyl aminopeptidase; InterPro IPR000819: IPR008283; KEGG: dat:HRM2_40450 PepA; PFAM: peptidase M17 leucyl aminopeptidase domain protein; PRIAM: Leucyl aminopeptidase; SPTR: Leucyl aminopeptidase; PFAM: Cytosol aminopeptidase family, catalytic domain; Cytosol aminopeptidase family, N-terminal domain.
       0.553
ADW17456.1
Pyridoxine 5'-phosphate synthase; COGs: COG0854 Pyridoxal phosphate biosynthesis protein; InterPro IPR002036: IPR004569: IPR020549; KEGG: dps:DP1605 pyridoxal phosphate biosynthetic protein; PFAM: Pyridoxal phosphate biosynthetic protein PdxJ; protein of unknown function UPF0054; PRIAM: Pyridoxine 5'-phosphate synthase; SPTR: Probable pyridoxal phosphate biosynthetic protein; TIGRFAM: pyridoxal phosphate biosynthetic protein PdxJ; PFAM: Pyridoxal phosphate biosynthesis protein PdxJ; Uncharacterized protein family UPF0054; TIGRFAM: metalloprotein, YbeY/UPF0054 family; pyridoxine 5'-phos [...]
  
  
 0.462
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.460
ADW18078.1
COGs: COG0225 Peptide methionine sulfoxide reductase; InterPro IPR002569: IPR002579; KEGG: tau:Tola_0999 methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; Methionine sulfoxide reductase A; PRIAM: Peptide-methionine (S)-S-oxide reductase., Peptide-methionine (R)-S-oxide reductase; SPTR: Methionine-R-sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; peptide methionine sulfoxide reductase; PFAM: SelR domain; Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase; methionine-R-sulfoxide reductase.
 
   
 0.460
ADW18458.1
Protein of unknown function DUF1058; InterPro IPR010466; KEGG: dal:Dalk_4331 SH3 type 3 domain protein; PFAM: protein of unknown function DUF1058; SPTR: SH3 type 3 domain protein; PFAM: Bacterial SH3 domain.
  
    0.438
fbp
D-fructose 1,6-bisphosphatase; COGs: COG0158 Fructose-1 6-bisphosphatase; InterPro IPR000146: IPR020548; KEGG: dak:DaAHT2_0468 inositol phosphatase/fructose-16-bisphosphatase; PFAM: Inositol phosphatase/fructose-16-bisphosphatase; SPTR: Inositol phosphatase/fructose-16-bisphosphatase; PFAM: Fructose-1-6-bisphosphatase; Belongs to the FBPase class 1 family.
       0.422
ADW18775.1
Exodeoxyribonuclease III Xth; COGs: COG0708 Exonuclease III; InterProIPR003265: IPR000097: IPR004808: IPR020847: IPR 020848: IPR004036: IPR003651: IPR005135; KEGG: dak:DaAHT2_1503 exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; HhH-GPD family protein; iron-sulfur cluster loop; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD family protein; SPTR: Exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; HhH-GPD superfamily base excision DNA repair protein; H [...]
 
    0.402
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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