STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18481.1CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR005467: IPR001789: IPR002545: IPR008207: IPR 003594: IPR004358; KEGG: nhl:Nhal_3349 response regulator receiver; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; Hpt domain protein; CheW domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; Hpt domain protein; CheW domain protein; SPTR: Sensor histidine kinase/response regulator; PFAM: CheW-like domain; Response regulator receiver domain; Histidin [...] (1147 aa)    
Predicted Functional Partners:
ADW17348.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 000700: IPR008207: IPR001610: IPR003661: IPR003594: IPR013656:I PR013767; KEGG: alv:Alvin_2605 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator re [...]
  
 
 0.991
ADW16317.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR001789: IPR000014: IPR001633: IPR000160: IPR 013767; KEGG: dak:DaAHT2_0284 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold domain protein; response regulator receiver; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; resp [...]
 
 
 0.990
ADW19133.1
Multi-sensor hybrid histidine kinase; COGs: COG3614 periplasmic ligand-binding sensor domain; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 006189: IPR013767: IPR013656: IPR003594: IPR004358: IPR001610; KEGG: gsu:GSU2816 sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; CHASE domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: PAS/PAC sensor [...]
  
 
0.990
ADW19026.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR003660: IPR003661: IPR 003594: IPR004358; KEGG: gbm:Gbem_3181 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SPTR: Hpt sensor hybrid histidine kinase; [...]
  
 
 0.987
ADW18652.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003018: IPR 003661: IPR003594: IPR001789: IPR008207: IPR005467: IPR000700:I PR013767: IPR013655: IPR013656; KEGG: alv:Alvin_0242 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain pro [...]
  
 
0.986
ADW18477.1
COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089: IPR003660: IPR004090; KEGG: cts:Ctha_2353 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: Methyl-accepting chemotaxis sensory transducer; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain.
 
 0.981
ADW17006.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dal:Dalk_1498 histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Histidine kinase; PFAM: Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.
 
 
 0.974
ADW17360.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 001610: IPR003018: IPR003661: IPR003594: IPR013767: IPR013656:I PR013655; KEGG: ppd:Ppro_3572 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS doma [...]
 
 
 0.974
ADW18650.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR003660: IPR000014: IPR001610: IPR 003661: IPR003594: IPR001789: IPR005467: IPR000700: IPR008207:I PR013655; KEGG: dba:Dbac_2628 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain contai [...]
  
 
 0.973
ADW17885.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014: IPR003018: IPR003661: IPR003594: IPR 001789: IPR013656: IPR013655: IPR004358: IPR005467: IPR000700; KEGG: dal:Dalk_4421 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; GAF domain protein; PAS domain containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: Multi-s [...]
  
 
 0.972
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.