STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18487.1COGs: COG0133 Tryptophan synthase beta chain; InterPro IPR001926: IPR006653: IPR006654; KEGG: dps:DP1631 tryptophan synthase subunit beta; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Probable tryptophan synthase, beta subunit; TIGRFAM: tryptophan synthase, beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: tryptophan synthase, beta subunit. (408 aa)    
Predicted Functional Partners:
ADW17567.1
COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: dak:DaAHT2_0450 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase.
 
 0.999
ADW18486.1
COGs: COG0159 Tryptophan synthase alpha chain; InterPro IPR002028: IPR018204; KEGG: dak:DaAHT2_1366 tryptophan synthase, alpha subunit; PFAM: tryptophan synthase alpha chain; SPTR: Tryptophan synthase, alpha subunit; TIGRFAM: tryptophan synthase, alpha subunit; PFAM: Tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, alpha subunit.
 0.999
ADW17566.1
COGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: dak:DaAHT2_0451 phosphoribosylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: Phosphoribosylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase.
  
 0.998
ADW17568.1
COGs: COG0547 Anthranilate phosphoribosyltransferase; InterPro IPR005940: IPR017459: IPR000312; KEGG: dps:DP1621 anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase family 3; Glycosyl transferase, family 3-like; SPTR: Anthranilate phosphoribosyltransferase; TIGRFAM: anthranilate phosphoribosyltransferase; PFAM: Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: anthranilate phosphoribosyltransferase.
  
 0.988
ADW17570.1
COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR005256: IPR006805: IPR015890: IPR019999; KEGG: dak:DaAHT2_0447 anthranilate synthase component I; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase component I; TIGRFAM: anthranilate synthase component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: anthranilate synthase component I, non-proteobacterial lineages.
 
  
 0.979
ADW17569.1
COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterProIPR006221: IPR017926: IPR000991: IPR006220: IPR 011702: IPR001317; KEGG: dps:DP1620 para-aminobenzoate/anthranilate synthase glutamine amidotransferase, component II; PFAM: glutamine amidotransferase class-I; SPTR: Probable para-aminobenzoate/anthranilate synthase glutamine amidotransferase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase.
  
 0.975
ADW18517.1
Pyridoxal-phosphate dependent TrpB-like enzyme; COGs: COG1350 alternative tryptophan synthase beta-subunit (paralog of TrpB); InterPro IPR001926: IPR006653: IPR006316; KEGG: dak:DaAHT2_0908 pyridoxal-phosphate dependent TrpB-like enzyme; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Tryptophan synthase; SPTR: Pyridoxal-phosphate dependent TrpB-like enzyme; TIGRFAM: pyridoxal-phosphate dependent TrpB-like enzyme; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: pyridoxal-phosphate dependent TrpB-like enzyme.
 
 
0.934
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.927
ADW18674.1
CDP-diacylglycerol--serine O-phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR004533: IPR000462; KEGG: dak:DaAHT2_0542 CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol/serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase.
     
  0.900
ADW18772.1
COGs: COG0682 Prolipoprotein diacylglyceryltransferase; InterPro IPR001640; KEGG: dak:DaAHT2_1973 prolipoprotein diacylglyceryl transferase; PFAM: prolipoprotein diacylglyceryl transferase; SPTR: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase; PFAM: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase.
  
    0.877
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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