STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18490.1InterPro IPR011138; KEGG: dol:Dole_1555 succinate dehydrogenase/fumarate reductase cytochrome b subunit; SPTR: Succinate dehydrogenase or fumarate reductase cytochrome b subunit, b558 family; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (218 aa)    
Predicted Functional Partners:
ADW18492.1
COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR017896: IPR006058: IPR017900; KEGG: dps:DP2137 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; SPTR: Probable succinate dehydrogenase, iron-sulfur protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
 
 
 0.999
ADW18491.1
COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953: IPR004112: IPR011280; KEGG: dps:DP2136 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Succinate dehydrogenase; SPTR: Probable succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup.
 
 
 0.998
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.975
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.975
ADW16573.1
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.920
ADW16228.1
Fumarase; COGs: COG0114 Fumarase; InterProIPR020557: IPR000362: IPR003031: IPR005677: IPR 018951; KEGG: dap:Dacet_2357 fumarate hydratase, class II; PFAM: fumarate lyase; Fumarase C-like; SPTR: Fumarate hydratase, class II; TIGRFAM: fumarate hydratase, class II; PFAM: Lyase; Fumarase C C-terminus; TIGRFAM: fumarate hydratase, class II.
     
  0.900
ADW18964.1
Succinate semialdehyde dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160: IPR010102; KEGG: rce:RC1_1593 succinate-semialdehyde dehydrogenase (NADP+); PFAM: Aldehyde Dehydrogenase; SPTR: Succinate-semialdehyde dehydrogenase (NADP+); TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase.
   
 
  0.900
aprA
Dissimilatory adenylylsulfate reductase alpha subunit precursor; COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR006076: IPR011803; KEGG: dak:DaAHT2_1471 adenylylsulfate reductase, alpha subunit; PFAM: FAD dependent oxidoreductase; SPTR: AprA; TIGRFAM: adenylylsulfate reductase, alpha subunit; PFAM: domain; FAD binding domain; TIGRFAM: adenosine phosphosulphate reductase, alpha subunit.
  
  
 0.841
ADW18677.1
Rieske (2Fe-2S) iron-sulfur domain protein; COGs: COG0723 Rieske Fe-S protein; InterPro IPR005805: IPR017941; KEGG: paa:Paes_1780 plastoquinol--plastocyanin reductase; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Cytochrome b6-f complex iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain.
   
  
 0.828
ADW16699.1
COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049: IPR003031: IPR000362: IPR020557; KEGG: dak:DaAHT2_2213 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
     
  0.800
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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