Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
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ADW18500.1COGs: COG2301 Citrate lyase beta subunit; InterPro IPR005000: IPR005479: IPR011206; KEGG: sfu:Sfum_2561 citrate (pro-3S)-lyase; PFAM: HpcH/HpaI aldolase; PRIAM: Citryl-CoA lyase; SPTR: Citrate (Pro-3S)-lyase; PFAM: HpcH/HpaI aldolase/citrate lyase family. (304 aa)    
Predicted Functional Partners:
ADW18658.1
L-carnitine dehydratase/bile acid-inducible protein F; COGs: COG1804 acyl-CoA transferase/carnitine dehydratase; InterPro IPR003673; KEGG: rca:Rcas_3518 L-carnitine dehydratase/bile acid-inducible protein F; PFAM: L-carnitine dehydratase/bile acid-inducible protein F; SPTR: L-carnitine dehydratase/bile acid-inducible protein F; PFAM: CoA-transferase family III.
 
  
 0.919
ADW18629.1
L-fuculose 1-phosphate aldolase; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: syg:sync_2475 L-fuculose phosphate aldolase; PFAM: class II aldolase/adducin family protein; SPTR: L-fuculose phosphate aldolase; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase.
   
    0.904
ADW18501.1
COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000089: IPR000891: IPR003379: IPR001882; KEGG: dal:Dalk_3782 conserved carboxylase region; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; SPTR: Conserved carboxylase region; PFAM: HMGL-like; Conserved carboxylase domain; Biotin-requiring enzyme.
  
  
 0.662
ADW18269.1
Lytic transglycosylase catalytic; InterPro IPR008258; KEGG: mca:MCA2115 transglycosylase SLT domain-containing protein; PFAM: Lytic transglycosylase catalytic; SPTR: Lytic transglycosylase catalytic; PFAM: Transglycosylase SLT domain.
  
     0.572
ADW16573.1
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.545
ADW19017.1
acetyl-CoA carboxylase, biotin carboxylase; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR000089: IPR011761: IPR011764: IPR005481: IPR 005479: IPR005482: IPR004549; KEGG: mpt:Mpe_A1017 propionyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: Propionyl-CoA carboxylase, alpha subunit; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase [...]
 
  
 0.544
ADW18147.1
Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterProIPR001891: IPR000209: IPR015884: IPR012301: IPR 012302; KEGG: dal:Dalk_0610 malate dehydrogenase; PFAM: malic protein NAD-binding; malic protein domain protein; SPTR: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
  
  
 0.509
ADW17315.1
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterProIPR006158: IPR005129: IPR006099: IPR006159: IPR 006098; KEGG: app:CAP2UW1_0492 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; ArgK protein; cobalamin B12-binding domain protein; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: ArgK protein; Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain.
  
  
 0.503
ADW19015.1
Sodium ion-translocating decarboxylase, beta subunit; COGs: COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; InterPro IPR005661; KEGG: dol:Dole_2282 sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; PRIAM: Oxaloacetate decarboxylase; SPTR: Sodium ion-translocating decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit.
 
  
 0.499
nifJ
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017896: IPR017900: IPR002880: IPR 019752: IPR019456: IPR011766; KEGG: dak:DaAHT2_0906 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavod [...]
  
  
 0.497
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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