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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
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gene co-occurrence
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[Homology]
Score
ADW18501.1COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000089: IPR000891: IPR003379: IPR001882; KEGG: dal:Dalk_3782 conserved carboxylase region; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; SPTR: Conserved carboxylase region; PFAM: HMGL-like; Conserved carboxylase domain; Biotin-requiring enzyme. (663 aa)    
Predicted Functional Partners:
ADW19015.1
Sodium ion-translocating decarboxylase, beta subunit; COGs: COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; InterPro IPR005661; KEGG: dol:Dole_2282 sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; PRIAM: Oxaloacetate decarboxylase; SPTR: Sodium ion-translocating decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit.
 
 
 0.998
ADW19017.1
acetyl-CoA carboxylase, biotin carboxylase; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR000089: IPR011761: IPR011764: IPR005481: IPR 005479: IPR005482: IPR004549; KEGG: mpt:Mpe_A1017 propionyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: Propionyl-CoA carboxylase, alpha subunit; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase [...]
 
0.994
nifJ
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017896: IPR017900: IPR002880: IPR 019752: IPR019456: IPR011766; KEGG: dak:DaAHT2_0906 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavod [...]
  
 
 0.968
ADW18893.1
COGs: COG0039 Malate/lactate dehydrogenase; InterPro IPR001557: IPR010945: IPR001236; KEGG: dps:DP0661 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase; SPTR: Malate dehydrogenase; TIGRFAM: malate dehydrogenase; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: malate dehydrogenase.
    
 0.953
ADW19113.1
Response regulator receiver protein; COGs: COG0469 Pyruvate kinase; InterPro IPR001789: IPR015793: IPR018209: IPR001697; KEGG: bbe:BBR47_13840 pyruvate kinase; PFAM: Pyruvate kinase barrel; response regulator receiver; SMART: response regulator receiver; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Response regulator receiver domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase.
  
 
 0.953
ADW19383.1
COGs: COG0469 Pyruvate kinase; InterPro IPR015793: IPR015794: IPR001697; KEGG: sfu:Sfum_2959 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase.
  
 
 0.951
ADW16249.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752: IPR002880; KEGG: dat:HRM2_42780 PorA3; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: PorA3; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit.
  
 
 0.949
ADW18147.1
Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterProIPR001891: IPR000209: IPR015884: IPR012301: IPR 012302; KEGG: dal:Dalk_0610 malate dehydrogenase; PFAM: malic protein NAD-binding; malic protein domain protein; SPTR: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
    
 0.942
ADW17655.1
COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR017597: IPR001017; KEGG: gur:Gura_1609 pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component; PRIAM: Pyruvate dehydrogenase (acetyl-transferring); SPTR: Pyruvate dehydrogenase (Acetyl-transferring); TIGRFAM: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit.
    
 0.938
ADW16250.1
2-oxoglutarate synthase; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: dat:HRM2_42790 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; PRIAM: 2-oxoglutarate synthase; SPTR: PorB4; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
  
 
 0.937
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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