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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18517.1Pyridoxal-phosphate dependent TrpB-like enzyme; COGs: COG1350 alternative tryptophan synthase beta-subunit (paralog of TrpB); InterPro IPR001926: IPR006653: IPR006316; KEGG: dak:DaAHT2_0908 pyridoxal-phosphate dependent TrpB-like enzyme; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Tryptophan synthase; SPTR: Pyridoxal-phosphate dependent TrpB-like enzyme; TIGRFAM: pyridoxal-phosphate dependent TrpB-like enzyme; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: pyridoxal-phosphate dependent TrpB-like enzyme. (447 aa)    
Predicted Functional Partners:
ADW18486.1
COGs: COG0159 Tryptophan synthase alpha chain; InterPro IPR002028: IPR018204; KEGG: dak:DaAHT2_1366 tryptophan synthase, alpha subunit; PFAM: tryptophan synthase alpha chain; SPTR: Tryptophan synthase, alpha subunit; TIGRFAM: tryptophan synthase, alpha subunit; PFAM: Tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, alpha subunit.
  
 0.999
ADW17567.1
COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: dak:DaAHT2_0450 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase.
 
 
 0.991
ADW18487.1
COGs: COG0133 Tryptophan synthase beta chain; InterPro IPR001926: IPR006653: IPR006654; KEGG: dps:DP1631 tryptophan synthase subunit beta; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Probable tryptophan synthase, beta subunit; TIGRFAM: tryptophan synthase, beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: tryptophan synthase, beta subunit.
 
 
0.934
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
  0.908
ADW18674.1
CDP-diacylglycerol--serine O-phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR004533: IPR000462; KEGG: dak:DaAHT2_0542 CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol/serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase.
     
  0.900
ADW16517.1
Transferase hexapeptide repeat containing protein; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: gbm:Gbem_1779 transferase hexapeptide repeat containing protein; SPTR: Transferase hexapeptide repeat containing protein; PFAM: Bacterial transferase hexapeptide (three repeats).
     
  0.800
ADW19119.1
COGs: COG2021 Homoserine acetyltransferase; InterPro IPR000073: IPR008220: IPR006296; KEGG: dol:Dole_0752 homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; PRIAM: Homoserine O-acetyltransferase; SPTR: Homoserine O-acetyltransferase; TIGRFAM: homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; TIGRFAM: homoserine O-acetyltransferase.
     
  0.800
ADW19121.1
COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: sfu:Sfum_2682 serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase.
     
  0.800
ADW18516.1
D-alanyl-D-alaninecarboxypeptidase/D-alanyl-D- alanine-endopeptidase; COGs: COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); InterPro IPR000667; KEGG: dps:DP2814 penicillin-binding protein 4 [precursor]; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: Peptidase S13, D-Ala-D-Ala carboxypeptidase C; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family.
       0.691
ADW17566.1
COGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: dak:DaAHT2_0451 phosphoribosylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: Phosphoribosylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase.
    
 0.645
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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