Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADW18527.1Protein of unknown function DUF2168; COGs: COG4752 conserved hypothetical protein; InterPro IPR019230; KEGG: dps:DP2804 hypothetical protein; PFAM: Protein of unknown function DUF2168; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2168). (209 aa)    
Predicted Functional Partners:
ADW18528.1
COGs: COG0336 tRNA-(guanine-N1)-methyltransferase; InterPro IPR002649: IPR016009; KEGG: dak:DaAHT2_1170 tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; PRIAM: tRNA (guanine-N(1)-)-methyltransferase; SPTR: tRNA (Guanine-N1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (Guanine-1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase.
 
  
 0.983
ADW18529.1
COGs: COG0806 RimM protein required for 16S rRNA processing; InterPro IPR011961: IPR002676: IPR007903; KEGG: ami:Amir_5924 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel domain protein; SPTR: Ribosome maturation factor rimM; TIGRFAM: 16S rRNA processing protein RimM; PFAM: PRC-barrel domain; RimM N-terminal domain; TIGRFAM: 16S rRNA processing protein RimM.
 
    0.828
rpsP
COGs: COG0228 Ribosomal protein S16; InterPro IPR000307: IPR020592; KEGG: dps:DP2800 30S ribosomal protein S16; PFAM: ribosomal protein S16; SPTR: 30S ribosomal protein S16; TIGRFAM: ribosomal protein S16; PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
     
 0.820
ADW18530.1
COGs: COG1837 RNA-binding protein (contains KH domain); InterPro IPR004088: IPR020627; KEGG: dba:Dbac_3306 RNA-binding protein (KH domain); SPTR: Putative uncharacterized protein.
       0.797
ADW18793.1
H+transporting two-sector ATPase B/B' subunit; InterPro IPR002146; KEGG: dps:DP0829 ATP synthase, subunit b' (AtpX); PFAM: H+transporting two-sector ATPase B/B' subunit; SPTR: Probable ATP synthase, subunit b' (AtpX); PFAM: ATP synthase B/B' CF(0).
  
    0.635
ffh
Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...]
       0.634
rplS
LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
     
 0.630
ADW18525.1
RNase HII; COGs: COG0164 Ribonuclease HII; InterPro IPR001352; KEGG: dps:DP2806 ribonuclease HII; PFAM: ribonuclease HII/HIII; PRIAM: Ribonuclease H; SPTR: Ribonuclease HII; PFAM: Ribonuclease HII.
     
 0.473
ADW16264.1
Radical SAM domain protein; COGs: COG1243 Histone acetyltransferase; InterPro IPR006638: IPR007197; KEGG: dps:DP1246 hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; PFAM: Radical SAM superfamily.
  
     0.443
ADW18524.1
Uncharacterized protein family UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509; KEGG: dak:DaAHT2_1166 protein of unknown function UPF0102; PFAM: Uncharacterised protein family UPF0102; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: conserved hypothetical protein TIGR00252.
       0.436
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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