Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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ADW18617.1Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006224: IPR006145; KEGG: dps:DP2730 ribosomal large subunit pseudouridine synthase D; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family. (302 aa)    
Predicted Functional Partners:
ADW17256.1
GTP-binding protein Obg/CgtA; COGs: COG0536 GTPase; InterProIPR006073: IPR014100: IPR006169: IPR002917: IPR 006074: IPR005225; KEGG: dps:DP2590 GTPase ObgE; PFAM: GTP1/OBG sub domain protein; GTP-binding protein HSR1-related; SPTR: GTPase obg; TIGRFAM: GTP-binding protein Obg/CgtA; small GTP-binding protein; PFAM: GTPase of unknown function; GTP1/OBG; TIGRFAM: Obg family GTPase CgtA; small GTP-binding protein domain.
 
 
 0.917
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
   0.816
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
 
 
 0.813
ADW18616.1
COGs: COG0237 Dephospho-CoA kinase; InterPro IPR001977; KEGG: dak:DaAHT2_0605 dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; PRIAM: Dephospho-CoA kinase; SPTR: Dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase.
       0.813
ADW18766.1
tRNA modification GTPase trmE; COGs: COG0486 GTPase; InterProIPR004520: IPR001806: IPR005225: IPR018948: IPR 002917; KEGG: dps:DP0857 tRNA modification GTPase TrmE; PFAM: GTP-binding protein TrmE-like; GTP-binding protein HSR1-related; SPTR: tRNA modification GTPase mnmE; TIGRFAM: tRNA modification GTPase TrmE; small GTP-binding protein; PFAM: GTPase of unknown function; GTP-binding protein TrmE N-terminus; TIGRFAM: small GTP-binding protein domain; tRNA modification GTPase TrmE.
 
 
 0.811
ADW18620.1
Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; COGs: COG1825 Ribosomal protein L25 (general stress protein Ctc); InterPro IPR001021: IPR020055; KEGG: dps:DP2733 50S ribosomal protein L25; PFAM: Ribosomal protein L25-like; SPTR: 50S ribosomal protein L25; TIGRFAM: ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; PFAM: Ribosomal L25p family; TIGRFAM: ribosomal protein L25, Ctc-form.
   
   0.795
ADW18334.1
Protein of unknown function DUF615; COGs: COG3028 conserved hypothetical protein; InterPro IPR006839; KEGG: dps:DP1679 hypothetical protein; PFAM: protein of unknown function DUF615; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF615).
    
 
 0.777
rplS
LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
 
 
 0.759
rplE
LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
 
 
   0.752
ADW18922.1
RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR013123: IPR001537: IPR004441; KEGG: dps:DP2859 tRNA/rRNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: Related to tRNA/rRNA methyltransferase; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3.
  
 
 0.748
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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