| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADW17084.1 | ADW17654.1 | Despr_0910 | Despr_1500 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: cpi:Cpin_0368 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475: IPR005476: IPR017871; KEGG: gur:Gura_1610 transketolase, central region; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: Transketolase, central region; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. | 0.905 |
| ADW17084.1 | ADW17682.1 | Despr_0910 | Despr_1528 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: cpi:Cpin_0368 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR005854: IPR017932: IPR000583; KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: amidophosphoribosyltransferase. | 0.923 |
| ADW17084.1 | ADW18156.1 | Despr_0910 | Despr_2008 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: cpi:Cpin_0368 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR000276: IPR004785: IPR003500; KEGG: dak:DaAHT2_1283 sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Sugar-phosphate isomerase, RpiB/LacA/LacB family; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family. | 0.926 |
| ADW17084.1 | ADW18620.1 | Despr_0910 | Despr_2482 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: cpi:Cpin_0368 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; COGs: COG1825 Ribosomal protein L25 (general stress protein Ctc); InterPro IPR001021: IPR020055; KEGG: dps:DP2733 50S ribosomal protein L25; PFAM: Ribosomal protein L25-like; SPTR: 50S ribosomal protein L25; TIGRFAM: ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; PFAM: Ribosomal L25p family; TIGRFAM: ribosomal protein L25, Ctc-form. | 0.817 |
| ADW17084.1 | ADW18739.1 | Despr_0910 | Despr_2603 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: cpi:Cpin_0368 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | UDP-N-acetylglucosamine pyrophosphorylase; COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); InterPro IPR000215: IPR005835: IPR001451; KEGG: dak:DaAHT2_0919 glucosamine-1-phosphate N-acetyltransferase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; SPTR: Glucosamine-1-phosphate N-acetyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase. | 0.779 |
| ADW17084.1 | ADW19128.1 | Despr_0910 | Despr_2995 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: cpi:Cpin_0368 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. | 0.996 |
| ADW17084.1 | hisG | Despr_0910 | Despr_1815 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: cpi:Cpin_0368 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.856 |
| ADW17084.1 | prs | Despr_0910 | Despr_2483 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: cpi:Cpin_0368 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.928 |
| ADW17084.1 | purF | Despr_0910 | Despr_2721 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: cpi:Cpin_0368 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.923 |
| ADW17084.1 | pyrE | Despr_0910 | Despr_1318 | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: cpi:Cpin_0368 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.851 |
| ADW17654.1 | ADW17084.1 | Despr_1500 | Despr_0910 | Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475: IPR005476: IPR017871; KEGG: gur:Gura_1610 transketolase, central region; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: Transketolase, central region; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: cpi:Cpin_0368 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | 0.905 |
| ADW17654.1 | ADW19128.1 | Despr_1500 | Despr_2995 | Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475: IPR005476: IPR017871; KEGG: gur:Gura_1610 transketolase, central region; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: Transketolase, central region; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. | 0.999 |
| ADW17654.1 | prs | Despr_1500 | Despr_2483 | Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475: IPR005476: IPR017871; KEGG: gur:Gura_1610 transketolase, central region; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: Transketolase, central region; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.905 |
| ADW17682.1 | ADW17084.1 | Despr_1528 | Despr_0910 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR005854: IPR017932: IPR000583; KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: amidophosphoribosyltransferase. | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: cpi:Cpin_0368 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | 0.923 |
| ADW17682.1 | ADW19128.1 | Despr_1528 | Despr_2995 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR005854: IPR017932: IPR000583; KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: amidophosphoribosyltransferase. | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. | 0.408 |
| ADW17682.1 | prs | Despr_1528 | Despr_2483 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR005854: IPR017932: IPR000583; KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: amidophosphoribosyltransferase. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.928 |
| ADW17682.1 | purF | Despr_1528 | Despr_2721 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR005854: IPR017932: IPR000583; KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: amidophosphoribosyltransferase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.924 |
| ADW17682.1 | pyrE | Despr_1528 | Despr_1318 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR005854: IPR017932: IPR000583; KEGG: sfu:Sfum_0268 amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: amidophosphoribosyltransferase. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.401 |
| ADW18156.1 | ADW17084.1 | Despr_2008 | Despr_0910 | COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR000276: IPR004785: IPR003500; KEGG: dak:DaAHT2_1283 sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Sugar-phosphate isomerase, RpiB/LacA/LacB family; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family. | Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: cpi:Cpin_0368 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. | 0.926 |
| ADW18156.1 | prs | Despr_2008 | Despr_2483 | COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR000276: IPR004785: IPR003500; KEGG: dak:DaAHT2_1283 sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Sugar-phosphate isomerase, RpiB/LacA/LacB family; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.926 |