STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18630.1Methylthioribose-1-phosphate isomerase; COGs: COG0182 translation initiation factor 2B subunit eIF-2B alpha/beta/delta family; InterPro IPR005251: IPR011559: IPR000649; KEGG: azl:AZL_002040 methylthioribose-1-phosphate isomerase; PFAM: initiation factor 2B related; PRIAM: S-methyl-5-thioribose-1-phosphate isomerase; SPTR: Methylthioribose-1-phosphate isomerase; TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: Initiation factor 2 subunit family; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized proteins; S-meth [...] (365 aa)    
Predicted Functional Partners:
ADW18629.1
L-fuculose 1-phosphate aldolase; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: syg:sync_2475 L-fuculose phosphate aldolase; PFAM: class II aldolase/adducin family protein; SPTR: L-fuculose phosphate aldolase; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase.
  
 0.984
ADW19071.1
COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: dps:DP0795 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Probable ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase.
  
   0.826
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
    0.555
ADW19374.1
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: dsa:Desal_2300 methylenetetrahydrofolate reductase (NAD(P)H); PFAM: methylenetetrahydrofolate reductase; PRIAM: Methylenetetrahydrofolate reductase (NAD(P)H); SPTR: Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase.
   
  
 0.529
ADW17065.1
Inosine guanosine and xanthosine phosphorylase family; COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR000845: IPR011268; KEGG: dak:DaAHT2_0643 purine nucleoside phosphorylase I, inosine and guanosine-specific; PFAM: purine or other phosphorylase family 1; SPTR: Inosine guanosine and xanthosine phosphorylase:Purine nucleoside phosphorylase I, inosine and guanosine-specific; TIGRFAM: inosine guanosine and xanthosine phosphorylase family; PFAM: Phosphorylase superfamily; TIGRFAM: inosine guanosine and xanthosine phosphorylase family.
 
  
 0.496
ADW18738.1
Homocysteine S-methyltransferase; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726; KEGG: dps:DP2201 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: Related to 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: Homocysteine S-methyltransferase.
   
  
 0.494
ffh
Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...]
  
    0.487
ADW18631.1
Histidine kinase; COGs: COG1639 signal transduction protein; InterProIPR004358: IPR003607: IPR003661: IPR003594: IPR 005467: IPR013976; KEGG: dat:HRM2_30910 fusion protein comosed of N:signal transduction protein - C:ATPase-like osmosensitive K+ channel histidine kinase; PFAM: Metal-dependent hydrolase HDOD; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; metal-dependent phosphohydrolase HD region; SPTR: Fusion protein comosed of N:signal transduction protein-C:ATPase-like o [...]
       0.483
ADW18737.1
COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR011822: IPR000489: IPR004223: IPR006158: IPR 003759; KEGG: dps:DP2202 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: Vitamin B12 dependent methionine synthase activation region; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; PRIAM: Methionine synthase; SPTR: Related to 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: Pterin binding enzyme; Vitamin B12 dependent methionine synthase, activation domain; B1 [...]
   
  
 0.454
ADW17166.1
Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR002701: IPR001086: IPR008242: IPR020822: IPR 002912: IPR018528; KEGG: dps:DP2171 P-protein; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Probable P-protein; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
     
 0.449
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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