Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW18633.1Signal peptide peptidase SppA, 67K type; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR004634: IPR004635: IPR002142; KEGG: rcu:RCOM_1902780 Protease, putative; PFAM: peptidase S49; SPTR: Protease IV, a signal peptide peptidase; TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type; signal peptide peptidase SppA, 67K type. (621 aa)    
Predicted Functional Partners:
ADW18271.1
COGs: COG0861 Membrane protein TerC possibly involved in tellurium resistance; InterPro IPR005496; KEGG: lch:Lcho_3292 integral membrane protein TerC; PFAM: Integral membrane protein TerC; SPTR: Integral membrane protein TerC; PFAM: Integral membrane protein TerC family.
 
    0.694
ADW18630.1
Methylthioribose-1-phosphate isomerase; COGs: COG0182 translation initiation factor 2B subunit eIF-2B alpha/beta/delta family; InterPro IPR005251: IPR011559: IPR000649; KEGG: azl:AZL_002040 methylthioribose-1-phosphate isomerase; PFAM: initiation factor 2B related; PRIAM: S-methyl-5-thioribose-1-phosphate isomerase; SPTR: Methylthioribose-1-phosphate isomerase; TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: Initiation factor 2 subunit family; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized proteins; S-meth [...]
  
    0.455
ADW19084.1
COGs: COG0342 Preprotein translocase subunit SecD; InterPro IPR003335: IPR005791: IPR005665; KEGG: dps:DP0806 protein-export membrane protein SecD; PFAM: SecD/SecF/SecDF export membrane protein; SPTR: Related to protein-export membrane protein SecD; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF; PFAM: Protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF.
  
   
 0.454
ADW18632.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR004358: IPR001789: IPR000014: IPR003661: IPR 003594: IPR005467: IPR013767; KEGG: sat:SYN_02213 signal transduction histidine kinase; PFAM: response regulator receiver; PAS fold domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: response regulator receiver; PAS domain containing protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: Signal transducti [...]
       0.427
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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