STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18648.1COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR003660: IPR000014: IPR003661: IPR 003594: IPR001789: IPR005467: IPR000700: IPR007892: IPR013767; KEGG: sfu:Sfum_2379 multi-sensor hybrid histidine kinase; PFAM: CHASE4 domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region [...] (984 aa)    
Predicted Functional Partners:
ADW18652.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003018: IPR 003661: IPR003594: IPR001789: IPR008207: IPR005467: IPR000700:I PR013767: IPR013655: IPR013656; KEGG: alv:Alvin_0242 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain pro [...]
 
 
0.994
ADW19468.1
Multi-sensor hybrid histidine kinase; COGs: COG3452 periplasmic ligand-binding sensor domain; InterProIPR006189: IPR013767: IPR013656: IPR013655: IPR 003661: IPR003594: IPR001789: IPR004358: IPR000014: IPR005467:I PR000700: IPR001610; KEGG: dol:Dole_1520 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; CHASE domain protein; PAS fold domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; [...]
 
 
0.989
ADW18650.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR003660: IPR000014: IPR001610: IPR 003661: IPR003594: IPR001789: IPR005467: IPR000700: IPR008207:I PR013655; KEGG: dba:Dbac_2628 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain contai [...]
 
 
0.988
ADW19133.1
Multi-sensor hybrid histidine kinase; COGs: COG3614 periplasmic ligand-binding sensor domain; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 006189: IPR013767: IPR013656: IPR003594: IPR004358: IPR001610; KEGG: gsu:GSU2816 sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; CHASE domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: PAS/PAC sensor [...]
 
 
0.978
ADW17360.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 001610: IPR003018: IPR003661: IPR003594: IPR013767: IPR013656:I PR013655; KEGG: ppd:Ppro_3572 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS doma [...]
 
 
0.975
ADW17885.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014: IPR003018: IPR003661: IPR003594: IPR 001789: IPR013656: IPR013655: IPR004358: IPR005467: IPR000700; KEGG: dal:Dalk_4421 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; GAF domain protein; PAS domain containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: Multi-s [...]
 
 
0.974
ADW17348.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 000700: IPR008207: IPR001610: IPR003661: IPR003594: IPR013656:I PR013767; KEGG: alv:Alvin_2605 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator re [...]
 
 
0.972
ADW16314.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 003594: IPR013767: IPR013655; KEGG: cli:Clim_1831 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; P [...]
 
 
0.971
ADW17261.1
Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR008207: IPR 003661: IPR003594; KEGG: pth:PTH_2386 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SPTR: Signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [...]
 
 
0.970
ADW17683.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014: IPR005467: IPR001789: IPR000700: IPR 013767: IPR003661: IPR003594: IPR001610: IPR004358; KEGG: dol:Dole_3265 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: PAS/PAC s [...]
 
 
0.969
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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