STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18665.1Domain of unknown function DUF1745; COGs: COG3287 conserved hypothetical protein; InterPro IPR013702: IPR019494; KEGG: hau:Haur_1269 hypothetical protein; PFAM: domain of unknown function DUF1745; FIST C domain; SPTR: Putative uncharacterized protein; PFAM: FIST C domain; FIST N domain. (388 aa)    
Predicted Functional Partners:
ADW17242.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 003594: IPR013656; KEGG: dak:DaAHT2_2397 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protei [...]
 
  
 0.596
ADW17352.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 003661: IPR003594: IPR013767; KEGG: dak:DaAHT2_1107 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Response regulator receiver; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90 [...]
  
  
 0.596
ADW17187.1
DNA methylase N-4/N-6 domain protein; InterPro IPR001091: IPR002941; KEGG: npu:Npun_F1051 hypothetical protein; PFAM: DNA methylase N-4/N-6 domain protein; SPTR: Putative uncharacterized protein; PFAM: DNA methylase.
  
     0.499
ADW16898.1
Adenylate/guanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789: IPR001054: IPR018297; KEGG: bja:blr2288 two-component hybrid sensor and regulator; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; SPTR: Adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain.
  
    0.489
ADW18842.1
COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789; KEGG: mth:MTH440 sensory transduction regulatory protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sensory transduction regulatory protein; PFAM: Response regulator receiver domain.
 
  
 0.434
ADW18698.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dba:Dbac_0319 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
  
    0.421
ADW16314.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 003594: IPR013767: IPR013655; KEGG: cli:Clim_1831 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; P [...]
 
  
 0.418
ADW16686.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: glo:Glov_0050 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two-component response transcriptional regulator (OmpR family); PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
    0.418
ADW17371.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: dat:HRM2_10430 transcriptional regulatory protein; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: DNA-binding response regulator ArlR; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
    0.418
ADW17809.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: pca:Pcar_0360 two component signal transduction response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component signal transduction response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
    0.418
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.