Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW18678.1Cytochrome b/b6 domain protein; COGs: COG1290 Cytochrome b subunit of the bc complex; InterPro IPR005797; KEGG: hoh:Hoch_3893 cytochrome b/b6 domain protein; PFAM: Cytochrome b/b6 domain; SPTR: Cytochrome b. (288 aa)    
Predicted Functional Partners:
ADW18677.1
Rieske (2Fe-2S) iron-sulfur domain protein; COGs: COG0723 Rieske Fe-S protein; InterPro IPR005805: IPR017941; KEGG: paa:Paes_1780 plastoquinol--plastocyanin reductase; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Cytochrome b6-f complex iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain.
 
 0.999
ADW18199.1
Proton-translocating NADH-quinone oxidoreductase, chain M; COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR003918: IPR010227: IPR001750; KEGG: ant:Arnit_2664 proton-translocating NADH-quinone oxidoreductase subunit M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M.
  
 
 0.952
ADW17752.1
NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR011538: IPR019554: IPR019575: IPR017896: IPR 017900; KEGG: dma:DMR_07840 putative NAD-reducing hydrogenase subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: Putative NAD-reducing hydrogenase subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4 [...]
  
 
 0.949
nuoH
NADH dehydrogenase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
   
 
 0.944
ADW17049.1
COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR001750: IPR003918: IPR010227; KEGG: dak:DaAHT2_1919 proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-ubiquinone oxidoreductase chain 4, amino terminus; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M.
   
 
 0.944
ADW18013.1
COGs: COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); InterPro IPR018086: IPR001694; KEGG: dds:Ddes_1661 NADH dehydrogenase (quinone); PFAM: respiratory-chain NADH dehydrogenase subunit 1; SPTR: NADH dehydrogenase (Quinone); PFAM: NADH dehydrogenase.
   
 
 0.944
ADW18018.1
COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR003918: IPR010227: IPR001750; KEGG: dds:Ddes_1656 proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M.
   
 
 0.944
ADW18204.1
COGs: COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); InterPro IPR018086: IPR001694; KEGG: abu:Abu_0308 NADH-quinone oxidoreductase, H subunit; PFAM: respiratory-chain NADH dehydrogenase subunit 1; SPTR: NADH dehydrogenase (Quinone); PFAM: NADH dehydrogenase.
   
 
 0.944
ADW17035.1
Hypothetical protein; InterPro IPR011031; KEGG: sse:Ssed_4024 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 0.943
ADW17050.1
Proton-translocating NADH-quinone oxidoreductase, chain N; COGs: COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); InterPro IPR001750: IPR010096; KEGG: dak:DaAHT2_1918 proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Proton-translocating NADH-quinone oxidoreductase, chain N; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N.
   
 
 0.924
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.