STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18707.1COGs: COG0460 Homoserine dehydrogenase; InterProIPR016204: IPR019811: IPR005106: IPR001342: IPR 002912; KEGG: dak:DaAHT2_0885 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; SPTR: Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. (434 aa)    
Predicted Functional Partners:
ADW17925.1
COGs: COG0527 Aspartokinase; InterProIPR005260: IPR001341: IPR001048: IPR002912: IPR 018042; KEGG: dak:DaAHT2_0808 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
 
 0.985
ADW17085.1
COGs: COG0136 Aspartate-semialdehyde dehydrogenase; InterProIPR000534: IPR012280: IPR011534: IPR012080: IPR 000319; KEGG: dat:HRM2_29180 aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase dimerisation region; Semialdehyde dehydrogenase NAD - binding; PRIAM: Aspartate-semialdehyde dehydrogenase; SPTR: Aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: aspartate-semialdehyde dehydrogenase, gamma-proteobacterial.
 
 0.977
ADW19119.1
COGs: COG2021 Homoserine acetyltransferase; InterPro IPR000073: IPR008220: IPR006296; KEGG: dol:Dole_0752 homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; PRIAM: Homoserine O-acetyltransferase; SPTR: Homoserine O-acetyltransferase; TIGRFAM: homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; TIGRFAM: homoserine O-acetyltransferase.
 
 
 0.975
ADW17064.1
COGs: COG0498 Threonine synthase; InterPro IPR001926: IPR004450: IPR000634; KEGG: gme:Gmet_1631 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Threonine synthase; SPTR: L-threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase.
 
 
 0.957
ADW16702.1
COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220: IPR005263: IPR020624: IPR020625; KEGG: dps:DP0432 dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; PRIAM: Dihydrodipicolinate synthase; SPTR: Dihydrodipicolinate synthase; TIGRFAM: dihydrodipicolinate synthase; PFAM: Dihydrodipicolinate synthetase family; TIGRFAM: dihydrodipicolinate synthase.
 
 
 0.950
ADW18827.1
COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786: IPR018300: IPR001544; KEGG: dps:DP0192 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched-chain-amino-acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II.
  
 
 0.905
ADW19369.1
NIL domain protein; InterPro IPR018449: IPR017896: IPR017900; KEGG: slp:Slip_0736 NIL domain protein; PFAM: NIL domain; SPTR: NIL domain protein; PFAM: Small subunit of acetolactate synthase; 4Fe-4S binding domain; NIL domain.
     
  0.900
ADW19370.1
Protein of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: tjr:TherJR_1173 protein of unknown function DUF39; PFAM: protein of unknown function DUF39; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function DUF39.
     
  0.900
ADW18737.1
COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR011822: IPR000489: IPR004223: IPR006158: IPR 003759; KEGG: dps:DP2202 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: Vitamin B12 dependent methionine synthase activation region; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; PRIAM: Methionine synthase; SPTR: Related to 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: Pterin binding enzyme; Vitamin B12 dependent methionine synthase, activation domain; B1 [...]
  
 
 0.898
ADW18862.1
COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR000277: IPR006235; KEGG: rrs:RoseRS_1758 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase.
 
 
 0.898
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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