STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18722.14-hydroxy-3-methylbut-2-enyl diphosphate reductase; COGs: COG0761 Penicillin tolerance protein; InterPro IPR003451; KEGG: acr:Acry_1832 hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; PRIAM: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; SPTR: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; TIGRFAM: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming). (306 aa)    
Predicted Functional Partners:
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
 
 
 0.985
ADW18548.1
COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: dps:DP2699 geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; SPTR: Probable geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase.
 
 
 0.934
ADW18853.1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; COGs: COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; InterPro IPR003526: IPR001228: IPR018294: IPR020555; KEGG: dps:DP0257 bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; PFAM: MECDP-synthase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: Bifunctional enzyme ispD/ispF; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: YgbB family; Uncharacterized pr [...]
 
   
 0.916
ADW16235.1
SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
 
  
 0.910
ADW18921.1
COGs: COG0539 Ribosomal protein S1; InterPro IPR003029: IPR000110; KEGG: pca:Pcar_2672 30S ribosomal protein S1; PFAM: RNA binding S1 domain protein; SPTR: SSU ribosomal protein S1P; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1.
 
  
 0.910
ADW19434.1
COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR011994; KEGG: dak:DaAHT2_2673 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
      0.902
ADW16996.1
COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; InterPro IPR013512: IPR013644: IPR003821; KEGG: dps:DP1160 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase domain-containing protein; PRIAM: 1-deoxy-D-xylulose-5-phosphate reductoisomerase; SPTR: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
 
   
 0.848
ADW17967.1
COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: dps:DP2641 peptidyl-prolyl cis-trans isomerase (FKBP-type); PFAM: peptidylprolyl isomerase FKBP-type; SPTR: Peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase.
  
  
 0.819
ADW18622.1
4-diphosphocytidyl-2C-methyl-D-erythritolkinase; COGs: COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; InterPro IPR004424: IPR006204: IPR013750; KEGG: sat:SYN_03046 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase.
 
   
 0.819
ADW18547.1
COGs: COG1154 Deoxyxylulose-5-phosphate synthase; InterPro IPR005477: IPR005475: IPR005476: IPR020826; KEGG: dps:DP2700 1-deoxy-D-xylulose-5-phosphate synthase; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: 1-deoxy-D-xylulose-5-phosphate synthase; TIGRFAM: deoxyxylulose-5-phosphate synthase; PFAM: Transketolase, C-terminal domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Transketolase, pyrimidine binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase.
  
 0.816
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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