STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18758.1COGs: COG1254 Acylphosphatase; InterPro IPR020456: IPR001792: IPR017968; KEGG: sfu:Sfum_1427 acylphosphatase; PFAM: acylphosphatase; SPTR: Acylphosphatase; PFAM: Acylphosphatase. (95 aa)    
Predicted Functional Partners:
ADW16563.1
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.922
ADW16615.1
COGs: COG0280 Phosphotransacetylase; InterPro IPR016475: IPR004614: IPR010766: IPR002505; KEGG: sdl:Sdel_1045 phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; DRTGG domain protein; PRIAM: Phosphate acetyltransferase; SPTR: Phosphate acetyltransferase; TIGRFAM: phosphate acetyltransferase; PFAM: DRTGG domain; Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase.
    
 0.922
ADW16562.1
COGs: COG0282 Acetate kinase; InterPro IPR004372: IPR000890; KEGG: drt:Dret_1034 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase family; TIGRFAM: acetate kinase.
     
 0.918
ADW16431.1
ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR011761: IPR003781: IPR013650; KEGG: dal:Dalk_2592 CoA-binding domain protein; PFAM: ATP-grasp domain protein; CoA-binding domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain.
     
  0.900
ADW17656.1
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873: IPR020845; KEGG: gur:Gura_1608 acetyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
     
  0.900
ADW18411.1
CoA-binding domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterProIPR011761: IPR003781: IPR005811: IPR013650: IPR 018087; KEGG: dak:DaAHT2_1111 CoA-binding domain protein; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain.
     
  0.900
acs
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
  0.900
ADW18759.1
COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); InterProIPR001679: IPR013840: IPR003583: IPR001357: IPR 018239: IPR013839: IPR004150: IPR004149: IPR000445; KEGG: dak:DaAHT2_2447 DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase adenylation; NAD-dependent DNA ligase OB-fold; helix-hairpin-helix motif; BRCT domain protein; PRIAM: DNA ligase (NAD(+)); SMART: NAD-dependent DNA ligase; Helix-hairpin-helix DNA-binding class 1; BRCT domain protein; SPTR: DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase OB-fold domain; [...]
       0.809
ADW18760.1
4-oxalocrotonate tautomerase; InterPro IPR004370; KEGG: saf:SULAZ_0206 hypothetical protein; PFAM: 4-oxalocrotonate tautomerase; SPTR: Putative isomerase; PFAM: Tautomerase enzyme; TIGRFAM: 4-oxalocrotonate tautomerase family enzyme.
       0.773
ADW18757.1
KEGG: dak:DaAHT2_2418 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.566
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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