Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ADW18766.1tRNA modification GTPase trmE; COGs: COG0486 GTPase; InterProIPR004520: IPR001806: IPR005225: IPR018948: IPR 002917; KEGG: dps:DP0857 tRNA modification GTPase TrmE; PFAM: GTP-binding protein TrmE-like; GTP-binding protein HSR1-related; SPTR: tRNA modification GTPase mnmE; TIGRFAM: tRNA modification GTPase TrmE; small GTP-binding protein; PFAM: GTPase of unknown function; GTP-binding protein TrmE N-terminus; TIGRFAM: small GTP-binding protein domain; tRNA modification GTPase TrmE. (463 aa)    
Predicted Functional Partners:
mnmG
Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
 
 0.997
ADW17082.1
Methyltransferase GidB; COGs: COG0357 S-adenosylmethionine-dependent methyltransferase involved in cell division; InterPro IPR003682; KEGG: dps:DP1283 glucose inhibited division protein B; PFAM: glucose inhibited division protein; SPTR: Ribosomal RNA small subunit methyltransferase G; TIGRFAM: methyltransferase GidB; PFAM: rRNA small subunit methyltransferase G; TIGRFAM: 16S rRNA methyltransferase GidB.
 
  
 0.940
ADW18922.1
RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR013123: IPR001537: IPR004441; KEGG: dps:DP2859 tRNA/rRNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: Related to tRNA/rRNA methyltransferase; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3.
 
 
 
 0.863
ADW18768.1
COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR013308: IPR019998: IPR020001; KEGG: dps:DP0855 hypothetical protein; PFAM: 60 kDa inner membrane insertion protein; SPTR: Conserved hypothetical membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; membrane protein insertase, YidC/Oxa1 family domain containing; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain; membrane protein insertase, YidC/Oxa1 family, N-terminal domain.
 
  
 0.841
ADW18767.1
COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: dps:DP0856 hypothetical protein; PFAM: single-stranded nucleic acid binding R3H domain-containing protein; SMART: single-stranded nucleic acid binding R3H domain-containing protein; SPTR: Putative uncharacterized protein; PFAM: R3H domain.
     
 0.837
ADW16510.1
Sugar transferase, PEP-CTERM system associated; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR017475: IPR017464: IPR003362: IPR010916; KEGG: dat:HRM2_19690 CpsE; PFAM: sugar transferase; SPTR: CpsE; TIGRFAM: sugar transferase, PEP-CTERM system associated; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; TIGRFAM: sugar transferase, PEP-CTERM system associated; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.
   
    0.835
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
 
 
 0.825
ADW17964.1
Ribosome biogenesis GTP-binding protein YsxC; COGs: COG0218 GTPase; InterPro IPR019987: IPR002917; KEGG: dps:DP2637 hypothetical protein; PFAM: GTP-binding protein HSR1-related; SPTR: Probable GTP-binding protein engB; TIGRFAM: ribosome biogenesis GTP-binding protein YsxC; PFAM: GTPase of unknown function; TIGRFAM: ribosome biogenesis GTP-binding protein YsxC/EngB; small GTP-binding protein domain.
    
 
 0.813
ADW18617.1
Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006224: IPR006145; KEGG: dps:DP2730 ribosomal large subunit pseudouridine synthase D; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family.
 
 
 0.811
ADW16980.1
COGs: COG0200 Ribosomal protein L15; InterPro IPR005749: IPR001196; KEGG: dps:DP1144 50S ribosomal protein L15; SPTR: 50S ribosomal protein L15; TIGRFAM: ribosomal protein L15; manually curated; PFAM: Ribosomal protein L18e/L15; TIGRFAM: ribosomal protein L15, bacterial/organelle.
  
 
 
 0.801
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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