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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18766.1tRNA modification GTPase trmE; COGs: COG0486 GTPase; InterProIPR004520: IPR001806: IPR005225: IPR018948: IPR 002917; KEGG: dps:DP0857 tRNA modification GTPase TrmE; PFAM: GTP-binding protein TrmE-like; GTP-binding protein HSR1-related; SPTR: tRNA modification GTPase mnmE; TIGRFAM: tRNA modification GTPase TrmE; small GTP-binding protein; PFAM: GTPase of unknown function; GTP-binding protein TrmE N-terminus; TIGRFAM: small GTP-binding protein domain; tRNA modification GTPase TrmE. (463 aa)    
Predicted Functional Partners:
mnmG
Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
 
 0.993
ADW17082.1
Methyltransferase GidB; COGs: COG0357 S-adenosylmethionine-dependent methyltransferase involved in cell division; InterPro IPR003682; KEGG: dps:DP1283 glucose inhibited division protein B; PFAM: glucose inhibited division protein; SPTR: Ribosomal RNA small subunit methyltransferase G; TIGRFAM: methyltransferase GidB; PFAM: rRNA small subunit methyltransferase G; TIGRFAM: 16S rRNA methyltransferase GidB.
 
  
 0.944
ADW18922.1
RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR013123: IPR001537: IPR004441; KEGG: dps:DP2859 tRNA/rRNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: Related to tRNA/rRNA methyltransferase; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3.
 
 
 
 0.939
ADW16980.1
COGs: COG0200 Ribosomal protein L15; InterPro IPR005749: IPR001196; KEGG: dps:DP1144 50S ribosomal protein L15; SPTR: 50S ribosomal protein L15; TIGRFAM: ribosomal protein L15; manually curated; PFAM: Ribosomal protein L18e/L15; TIGRFAM: ribosomal protein L15, bacterial/organelle.
  
 
 
 0.931
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
 
 
 0.926
ADW17964.1
Ribosome biogenesis GTP-binding protein YsxC; COGs: COG0218 GTPase; InterPro IPR019987: IPR002917; KEGG: dps:DP2637 hypothetical protein; PFAM: GTP-binding protein HSR1-related; SPTR: Probable GTP-binding protein engB; TIGRFAM: ribosome biogenesis GTP-binding protein YsxC; PFAM: GTPase of unknown function; TIGRFAM: ribosome biogenesis GTP-binding protein YsxC/EngB; small GTP-binding protein domain.
    
 
 0.913
rplK
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.909
rplQ
COGs: COG0203 Ribosomal protein L17; InterPro IPR000456; KEGG: dak:DaAHT2_1424 ribosomal protein L17; PFAM: ribosomal protein L17; SPTR: Ribosomal protein L17; TIGRFAM: ribosomal protein L17; manually curated; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17.
  
 
   0.905
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
    
 
 0.899
ADW17100.1
Peptidylprolyl isomerase; COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130: IPR001179: IPR020892; KEGG: dps:DP1645 peptidyl-prolyl cis-trans isomerase; PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; peptidylprolyl isomerase FKBP-type; PRIAM: Peptidylprolyl isomerase; SPTR: Probable peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD.
   
   0.898
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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