STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18784.1Histidine triad (HIT) protein; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: dps:DP0841 hypothetical protein; PFAM: histidine triad (HIT) protein; SPTR: Putative uncharacterized protein; PFAM: HIT domain. (168 aa)    
Predicted Functional Partners:
ADW16545.1
COGs: COG2046 ATP sulfurylase (sulfate adenylyltransferase); InterPro IPR002891: IPR002650; KEGG: drt:Dret_2034 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; PFAM: ATP-sulfurylase; adenylylsulfate kinase; PRIAM: Sulfate adenylyltransferase., Adenylyl-sulfate kinase; SPTR: Adenylylsulfate kinase; TIGRFAM: adenylylsulfate kinase; PFAM: ATP-sulfurylase; Adenylylsulphate kinase; TIGRFAM: adenylylsulfate kinase (apsK); ATP sulphurylase.
    
 0.902
sat
COGs: COG2046 ATP sulfurylase (sulfate adenylyltransferase); InterPro IPR002650; KEGG: dps:DP1472 sulfate adenylyltransferase; PFAM: ATP-sulfurylase; PRIAM: Sulfate adenylyltransferase; SPTR: Probable sulfate adenylyltransferase; TIGRFAM: sulfate adenylyltransferase; PFAM: ATP-sulfurylase; TIGRFAM: ATP sulphurylase.
     
  0.900
ADW18402.1
COGs: COG0529 Adenylylsulfate kinase and related kinase; InterPro IPR002891; KEGG: alv:Alvin_1127 adenylylsulfate kinase; PFAM: adenylylsulfate kinase; PRIAM: Adenylyl-sulfate kinase; SPTR: Adenylylsulfate kinase; TIGRFAM: adenylylsulfate kinase; PFAM: Adenylylsulphate kinase; TIGRFAM: adenylylsulfate kinase (apsK).
     
  0.900
ADW18785.1
COGs: COG0249 Mismatch repair ATPase (MutS family); InterProIPR005748: IPR007696: IPR000432: IPR007695: IPR 007860: IPR007861; KEGG: dps:DP0840 DNA mismatch repair protein MutS; PFAM: MutS III domain protein; DNA mismatch repair protein MutS domain protein; MutS II domain protein; MutS IV domain protein; SMART: DNA mismatch repair protein MutS domain protein; MutS III domain protein; SPTR: DNA mismatch repair protein mutS; TIGRFAM: DNA mismatch repair protein MutS; PFAM: MutS family domain IV; MutS domain II; MutS domain V; MutS domain I; MutS domain III; TIGRFAM: DNA mismatch repair p [...]
     
 0.816
ADW18783.1
Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR000979: IPR004843; KEGG: dps:DP0842 hypothetical protein; PFAM: metallophosphoesterase; SPTR: Putative uncharacterized protein; TIGRFAM: phosphodiesterase, MJ0936 family; TIGRFAM: phosphoesterase, MJ0936 family.
  
    0.809
ADW19029.1
Type III restriction protein res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014021: IPR001650: IPR006935: IPR014001; KEGG: dak:DaAHT2_0092 type III restriction protein res subunit; PFAM: type III restriction protein res subunit; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Type III restriction protein res subunit; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit.
  
 
  0.786
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.768
thrS
Ser-tRNA(Thr) hydrolase; COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR002320: IPR006195: IPR012947: IPR002314: IPR 004154: IPR018158; KEGG: dak:DaAHT2_1245 threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Threonyl/alanyl tRNA synthetase SAD; Anticodon-binding domain protein; SPTR: Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase; Belongs to the class-II aminoacyl- [...]
    
 0.762
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
  0.740
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.739
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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