STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18842.1COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789; KEGG: mth:MTH440 sensory transduction regulatory protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sensory transduction regulatory protein; PFAM: Response regulator receiver domain. (120 aa)    
Predicted Functional Partners:
ADW18652.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003018: IPR 003661: IPR003594: IPR001789: IPR008207: IPR005467: IPR000700:I PR013767: IPR013655: IPR013656; KEGG: alv:Alvin_0242 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain pro [...]
  
 
 0.988
ADW19026.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR003660: IPR003661: IPR 003594: IPR004358; KEGG: gbm:Gbem_3181 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SPTR: Hpt sensor hybrid histidine kinase; [...]
  
 
 0.974
ADW16314.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 003594: IPR013767: IPR013655; KEGG: cli:Clim_1831 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; P [...]
 
 
 0.973
ADW17242.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 003594: IPR013656; KEGG: dak:DaAHT2_2397 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protei [...]
  
 
 0.971
ADW17262.1
Response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor; COGs: COG2199 FOG: GGDEF domain; InterProIPR001789: IPR000014: IPR000700: IPR000160: IPR 001610: IPR013767; KEGG: mpt:Mpe_A2857 sensory box/response regulator; PFAM: GGDEF domain containing protein; response regulator receiver; PAS fold domain protein; SMART: GGDEF domain containing protein; response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; SPTR: Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: diguanylate cy [...]
  
 
 0.971
ADW17352.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 003661: IPR003594: IPR013767; KEGG: dak:DaAHT2_1107 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Response regulator receiver; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90 [...]
  
 
 0.971
ADW18481.1
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR005467: IPR001789: IPR002545: IPR008207: IPR 003594: IPR004358; KEGG: nhl:Nhal_3349 response regulator receiver; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; Hpt domain protein; CheW domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; Hpt domain protein; CheW domain protein; SPTR: Sensor histidine kinase/response regulator; PFAM: CheW-like domain; Response regulator receiver domain; Histidin [...]
  
 
 0.971
ADW19128.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
   
 0.971
ADW19468.1
Multi-sensor hybrid histidine kinase; COGs: COG3452 periplasmic ligand-binding sensor domain; InterProIPR006189: IPR013767: IPR013656: IPR013655: IPR 003661: IPR003594: IPR001789: IPR004358: IPR000014: IPR005467:I PR000700: IPR001610; KEGG: dol:Dole_1520 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; CHASE domain protein; PAS fold domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; [...]
  
 
 0.970
ADW17348.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 000700: IPR008207: IPR001610: IPR003661: IPR003594: IPR013656:I PR013767; KEGG: alv:Alvin_2605 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator re [...]
  
 
 0.967
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.