Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
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ADW18843.1COGs: COG0686 Alanine dehydrogenase; InterPro IPR008141: IPR008143: IPR007886: IPR007698; KEGG: gbm:Gbem_1176 alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; PRIAM: Alanine dehydrogenase; SPTR: Alanine dehydrogenase; TIGRFAM: alanine dehydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase. (376 aa)    
Predicted Functional Partners:
ADW18093.1
COGs: COG0787 Alanine racemase; InterPro IPR000821: IPR020622: IPR001608: IPR011079; KEGG: dak:DaAHT2_1666 alanine racemase; PFAM: alanine racemase domain protein; PRIAM: Alanine racemase; SPTR: Alanine racemase; TIGRFAM: alanine racemase; PFAM: Alanine racemase, C-terminal domain; Alanine racemase, N-terminal domain; TIGRFAM: alanine racemase.
  
 
 0.977
ADW17096.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176: IPR004839; KEGG: dak:DaAHT2_1654 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II.
     
 0.911
ADW18513.1
Putative transcriptional regulator, GntR family; COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: pmo:Pmob_1584 GntR family transcriptional regulator; PFAM: aminotransferase class I and II; SPTR: Putative transcriptional regulator, GntR family; PFAM: Aminotransferase class I and II.
    
 0.902
nifJ
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017896: IPR017900: IPR002880: IPR 019752: IPR019456: IPR011766; KEGG: dak:DaAHT2_0906 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavod [...]
    
 0.885
ADW16249.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752: IPR002880; KEGG: dat:HRM2_42780 PorA3; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: PorA3; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit.
     
 0.837
ADW19113.1
Response regulator receiver protein; COGs: COG0469 Pyruvate kinase; InterPro IPR001789: IPR015793: IPR018209: IPR001697; KEGG: bbe:BBR47_13840 pyruvate kinase; PFAM: Pyruvate kinase barrel; response regulator receiver; SMART: response regulator receiver; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Response regulator receiver domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase.
    
 0.829
ADW19383.1
COGs: COG0469 Pyruvate kinase; InterPro IPR015793: IPR015794: IPR001697; KEGG: sfu:Sfum_2959 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase.
     
 0.826
ADW18190.1
COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192: IPR008279; KEGG: dat:HRM2_16260 PpsA4; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; SPTR: Pyruvate phosphate dikinase PEP/pyruvate-binding; PFAM: PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain.
     
 0.822
ADW18832.1
Pyruvate phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192: IPR008279; KEGG: dak:DaAHT2_2096 pyruvate phosphate dikinase PEP/pyruvate-binding protein; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; SPTR: Pyruvate phosphate dikinase PEP/pyruvate-binding protein; PFAM: PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain.
     
 0.822
ADW18947.1
COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR002192: IPR008279: IPR000121: IPR018274: IPR 006319; KEGG: dak:DaAHT2_0891 phosphoenolpyruvate synthase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; SPTR: Phosphoenolpyruvate synthase; TIGRFAM: phosphoenolpyruvate synthase; PFAM: PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: phosphoenolpyruvate synthase.
     
 0.822
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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