STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18848.1Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607: IPR006674; KEGG: aba:Acid345_4403 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; PFAM: HD domain. (418 aa)    
Predicted Functional Partners:
ADW16756.1
Putative PAS/PAC sensor protein; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR000014: IPR013767: IPR006674; KEGG: dat:HRM2_20440 two component protein (transcriptional response regulator/sensory box); PFAM: metal-dependent phosphohydrolase HD sub domain; PAS fold domain protein; SPTR: Two component protein (Transcriptional response regulator/sensory box); TIGRFAM: PAS sensor protein; PFAM: HD domain; PAS fold; TIGRFAM: PAS domain S-box.
 
  
 0.796
ADW19430.1
Response regulator receiver modulated metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789: IPR006674: IPR006675: IPR003607; KEGG: dps:DP0645 Ntr family protein two-component system response regulator; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region; SPTR: Related to two-component system response regulator (Ntr family); TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; Res [...]
 
    0.780
ADW18651.1
Response regulator receiver modulated metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789: IPR003607: IPR006674; KEGG: app:CAP2UW1_2767 response regulator receiver modulated metal dependent phosphohydrolase; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region; SPTR: Response regulator receiver modulated metal dependent phosphohydrolase; PFAM: HD domain; Response regulator receiver domain.
 
    0.769
ADW17935.1
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: azl:AZL_024270 two-component response regulator, modulated diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: Two-component response regulator, modulated diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
   
 0.693
ADW17724.1
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: gsu:GSU1643 GGDEF/response regulator receiver domain-containing protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: GGDEF/response regulator receiver domain protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
 
 0.688
ADW18652.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003018: IPR 003661: IPR003594: IPR001789: IPR008207: IPR005467: IPR000700:I PR013767: IPR013655: IPR013656; KEGG: alv:Alvin_0242 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain pro [...]
 
   
 0.603
ADW17910.1
Diguanylate cyclase with PAS/PAC sensor and hemerythrin-like metal-binding domain protein; COGs: COG2199 FOG: GGDEF domain; InterProIPR000014: IPR000160: IPR012827: IPR001610: IPR 013767: IPR012312: IPR000700: IPR016131; KEGG: asa:ASA_2981 GGDEF domain-containing protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; Hemerythrin HHE cation binding domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: GGDEF domain protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; hemerythrin-like metal-bindi [...]
 
 
 0.596
ADW17377.1
Diguanylate cyclase with PAS/PAC sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000014: IPR000160: IPR013767; KEGG: pca:Pcar_2296 GGDEF domain-containing protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: FOG: GGDEF domain protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
 
 
 0.589
ADW18846.1
5'-nucleotidase; COGs: COG0496 acid phosphatase; InterPro IPR002828; KEGG: dak:DaAHT2_2449 stationary-phase survival protein SurE; PFAM: Survival protein SurE; SPTR: Stationary-phase survival protein SurE; TIGRFAM: stationary-phase survival protein SurE; PFAM: Survival protein SurE; TIGRFAM: 5'/3'-nucleotidase SurE.
 
     0.589
ADW17390.1
Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR000160: IPR000644; KEGG: pin:Ping_2411 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; CBS domain containing protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
 0.586
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.