STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18854.1Peptidase T-like protein; COGs: COG2195 Di- and tripeptidase; InterPro IPR010162: IPR002933: IPR011650; KEGG: dps:DP0258 hypothetical protein; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: peptidase T-like protein; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: peptidase T-like protein. (381 aa)    
Predicted Functional Partners:
ADW18853.1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; COGs: COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; InterPro IPR003526: IPR001228: IPR018294: IPR020555; KEGG: dps:DP0257 bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; PFAM: MECDP-synthase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: Bifunctional enzyme ispD/ispF; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: YgbB family; Uncharacterized pr [...]
       0.822
ADW18850.1
Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: dps:DP0634 hypothetical protein; PFAM: protein of unknown function DUF34; SPTR: Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family.
 
    0.641
ADW17154.1
COGs: COG0030 Dimethyladenosine transferase (rRNA methylation); InterPro IPR020598: IPR001737: IPR011530: IPR020596; KEGG: dak:DaAHT2_0616 dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase; SMART: Ribosomal RNA adenine methylase transferase-like; SPTR: Dimethyladenosine transferase; TIGRFAM: dimethyladenosine transferase; PFAM: Ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase.
    
 0.638
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.522
ADW16774.1
Sun protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR004573: IPR006027: IPR001678: IPR018314; KEGG: dak:DaAHT2_2304 sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: Fmu, rRNA SAM-dependent methyltransferase; TIGRFAM: sun protein; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB.
 
   
 0.522
ADW16573.1
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
    0.521
ADW18078.1
COGs: COG0225 Peptide methionine sulfoxide reductase; InterPro IPR002569: IPR002579; KEGG: tau:Tola_0999 methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; Methionine sulfoxide reductase A; PRIAM: Peptide-methionine (S)-S-oxide reductase., Peptide-methionine (R)-S-oxide reductase; SPTR: Methionine-R-sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; peptide methionine sulfoxide reductase; PFAM: SelR domain; Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase; methionine-R-sulfoxide reductase.
     
 0.469
ADW17999.1
COGs: COG1345 Flagellar capping protein; InterPro IPR003481: IPR010809; KEGG: pca:Pcar_1112 flagellar biosynthesis filament capping protein, enables filament assembly; PFAM: flagellar hook-associated 2 domain-containing protein; flagellar hook-associated protein 2 domain-containing protein; SPTR: Flagellar biosynthesis filament capping protein, enables filament assembly; PFAM: Flagellar hook-associated protein 2 C-terminus.
   
   0.430
ADW18311.1
COGs: COG1345 Flagellar capping protein; InterPro IPR003481: IPR010810: IPR010809; KEGG: pca:Pcar_1112 flagellar biosynthesis filament capping protein, enables filament assembly; PFAM: flagellar hook-associated 2 domain-containing protein; flagellar hook-associated protein 2 domain-containing protein; flagellin hook IN repeat protein; SPTR: Flagellar biosynthesis filament capping protein, enables filament assembly; PFAM: Flagellar hook-associated protein 2 C-terminus.
   
   0.430
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.405
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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