STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18855.1COGs: COG0709 Selenophosphate synthase; Contains Selenocysteine; InterPro IPR004536: IPR000421: IPR000728: IPR010918; KEGG: ppd:Ppro_1707 selenide, water dikinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; SPTR: Selenide water dikinase; TIGRFAM: selenide, water dikinase; manually curated; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: selenium donor protein. (354 aa)    
Predicted Functional Partners:
ADW18474.1
COGs: COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]; InterPro IPR004534: IPR018319; KEGG: dak:DaAHT2_0215 L-seryl-tRNA selenium transferase; PFAM: Pyridoxal phosphate-dependent transferase; PRIAM: L-seryl-tRNA(Sec) selenium transferase; SPTR: L-seryl-tRNA selenium transferase; TIGRFAM: L-seryl-tRNA selenium transferase; PFAM: L-seryl-tRNA selenium transferase; TIGRFAM: seryl-tRNA(sec) selenium transferase.
 
  
 0.986
nifS
Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
    
 0.925
ADW17792.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0492 Thioredoxin reductase; InterPro IPR013027: IPR000103: IPR008255; KEGG: afl:Aflv_2528 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
     
 0.913
ADW18333.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0492 Thioredoxin reductase; InterPro IPR000103: IPR013027: IPR019825; KEGG: dak:DaAHT2_0308 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
     
 0.913
ADW19089.1
COGs: COG0492 Thioredoxin reductase; InterPro IPR013027: IPR000103: IPR008255: IPR005982; KEGG: dps:DP0809 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
     
 0.913
ADW17215.1
COGs: COG3276 Selenocysteine-specific translation elongation factor; InterProIPR000795: IPR004161: IPR015190: IPR015191: IPR 013838: IPR005225: IPR004535; KEGG: dak:DaAHT2_0324 selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 2; Elongation factor SelB winged helix 3; SPTR: Translation elongation factor, selenocysteine-specific:Small GTP-binding protein domain; TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: Elongat [...]
 
   
 0.868
ADW16487.1
Selenium metabolism protein YedF; InterPro IPR019870: IPR001455; KEGG: pca:Pcar_0303 redox protein, regulator of disulfide bond formation; PFAM: SirA-like domain-containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: selenium metabolism protein YedF; PFAM: SirA-like protein; DsrE/DsrF-like family; TIGRFAM: selenium metabolism protein YedF.
 
   
 0.840
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
    0.511
ADW19229.1
COGs: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit BcrC/BadD/HgdB; InterPro IPR010327; KEGG: aeh:Mlg_0785 2-hydroxyglutaryl-CoA dehydratase, D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase D-component; SPTR: 2-hydroxyglutaryl-CoA dehydratase, D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component.
 
     0.466
ADW18857.1
Hypothetical protein; InterPro IPR001080: IPR017896; KEGG: dma:DMR_00460 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1271).
       0.464
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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