STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18864.1Lipoic acid synthetase; COGs: COG0320 Lipoate synthase; InterPro IPR003698: IPR006638: IPR007197; KEGG: dps:DP0296 lipoyl synthase; PFAM: Radical SAM domain protein; PRIAM: Lipoyl synthase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Lipoyl synthase; TIGRFAM: lipoic acid synthetase; PFAM: Radical SAM superfamily; TIGRFAM: lipoate synthase. (295 aa)    
Predicted Functional Partners:
ADW18865.1
COGs: COG0321 Lipoate-protein ligase B; InterPro IPR000544: IPR020605: IPR004143; KEGG: dps:DP0297 lipoate-protein ligase B (LipB); PFAM: biotin/lipoate A/B protein ligase; PRIAM: Lipoyl(octanoyl) transferase; SPTR: Octanoyltransferase; TIGRFAM: lipoate-protein ligase B; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: lipoate-protein ligase B.
 
 0.999
ADW17651.1
COGs: COG0321 Lipoate-protein ligase B; InterPro IPR000544: IPR004143; KEGG: gur:Gura_1269 lipoate-protein ligase B; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Lipoyl(octanoyl) transferase; SPTR: Octanoyltransferase; TIGRFAM: lipoate-protein ligase B; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: lipoate-protein ligase B.
 
 0.998
ADW18868.1
COGs: COG0509 Glycine cleavage system H protein (lipoate-binding); InterPro IPR002930: IPR017453: IPR003016; KEGG: dps:DP0300 glycine cleavage system, H protein; PFAM: glycine cleavage H-protein; SPTR: Glycine cleavage system H protein; TIGRFAM: glycine cleavage system H protein; PFAM: Glycine cleavage H-protein; TIGRFAM: glycine cleavage system H protein.
 
 
 0.970
ADW18866.1
Glycine dehydrogenase (decarboxylating) beta subunit; COGs: COG1003 Glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; InterPro IPR020580; KEGG: dps:DP0298 glycine dehydrogenase subunit 2; PFAM: Glycine cleavage system P-protein-like; SPTR: Probable glycine dehydrogenase, subunit 2; PFAM: Glycine cleavage system P-protein.
  
  
 0.812
ADW18869.1
COGs: COG0404 Glycine cleavage system T protein (aminomethyltransferase); InterPro IPR006222; KEGG: dps:DP0301 glycine cleavage system, T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); SPTR: Related to glycine cleavage system, T protein; PFAM: Aminomethyltransferase folate-binding domain.
 
   
 0.793
ADW18867.1
Glycine dehydrogenase (decarboxylating) alpha subunit; COGs: COG0403 Glycine cleavage system protein P (pyridoxal-binding) N-terminal domain; InterPro IPR020580; KEGG: dps:DP0299 glycine dehydrogenase subunit 1; PFAM: Glycine cleavage system P-protein-like; PRIAM: Glycine dehydrogenase (decarboxylating); SPTR: Probable glycine dehydrogenase [decarboxylating] subunit 1; PFAM: Glycine cleavage system P-protein.
     
 0.791
ADW19128.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
  
 0.710
ADW18870.1
Transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR019888: IPR000485: IPR019887; KEGG: dps:DP0302 transcription regulator; PFAM: Transcription regulator AsnC-type-like; SMART: Transcription regulator AsnC-type; SPTR: Related to transcription regulator; PFAM: AsnC family.
       0.686
nifU
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
 
 0.506
ADW18863.1
KEGG: dps:DP0721 hypothetical protein; SPTR: Putative uncharacterized protein.
     
 0.501
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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