Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW18865.1COGs: COG0321 Lipoate-protein ligase B; InterPro IPR000544: IPR020605: IPR004143; KEGG: dps:DP0297 lipoate-protein ligase B (LipB); PFAM: biotin/lipoate A/B protein ligase; PRIAM: Lipoyl(octanoyl) transferase; SPTR: Octanoyltransferase; TIGRFAM: lipoate-protein ligase B; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: lipoate-protein ligase B. (232 aa)    
Predicted Functional Partners:
ADW18864.1
Lipoic acid synthetase; COGs: COG0320 Lipoate synthase; InterPro IPR003698: IPR006638: IPR007197; KEGG: dps:DP0296 lipoyl synthase; PFAM: Radical SAM domain protein; PRIAM: Lipoyl synthase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Lipoyl synthase; TIGRFAM: lipoic acid synthetase; PFAM: Radical SAM superfamily; TIGRFAM: lipoate synthase.
 
 0.999
ADW18868.1
COGs: COG0509 Glycine cleavage system H protein (lipoate-binding); InterPro IPR002930: IPR017453: IPR003016; KEGG: dps:DP0300 glycine cleavage system, H protein; PFAM: glycine cleavage H-protein; SPTR: Glycine cleavage system H protein; TIGRFAM: glycine cleavage system H protein; PFAM: Glycine cleavage H-protein; TIGRFAM: glycine cleavage system H protein.
   
 0.938
ADW17651.1
COGs: COG0321 Lipoate-protein ligase B; InterPro IPR000544: IPR004143; KEGG: gur:Gura_1269 lipoate-protein ligase B; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Lipoyl(octanoyl) transferase; SPTR: Octanoyltransferase; TIGRFAM: lipoate-protein ligase B; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: lipoate-protein ligase B.
  
  
 
0.917
ADW17111.1
Short-chain dehydrogenase/reductase SDR; COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR002347: IPR002198; KEGG: bts:Btus_2604 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
     
  0.800
fabF
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
     
  0.800
ADW18799.1
Enoyl-(acyl-carrier-protein) reductase (NADH); COGs: COG0623 Enoyl-(acyl-carrier-protein); KEGG: dps:DP0923 enoyl-[acyl-carrier-protein] reductase [NADH]; SPTR: Related to enoyl-[acyl-carrier-protein] reductase [NADH]; PFAM: short chain dehydrogenase.
     
  0.800
ADW18806.1
Beta-ketoacyl synthase; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR018506: IPR018201: IPR014030: IPR014031; KEGG: dps:DP2403 3-oxoacyl-[acyl-carrier-protein] synthase; PFAM: Beta-ketoacyl synthase; SPTR: Related to 3-oxoacyl-[acyl-carrier-protein] synthase; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
     
  0.800
ADW19140.1
COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030: IPR014031: IPR018201; KEGG: cja:CJA_0749 beta-ketoacyl-ACP synthase I; PFAM: Beta-ketoacyl synthase; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase I; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
     
  0.800
ADW18867.1
Glycine dehydrogenase (decarboxylating) alpha subunit; COGs: COG0403 Glycine cleavage system protein P (pyridoxal-binding) N-terminal domain; InterPro IPR020580; KEGG: dps:DP0299 glycine dehydrogenase subunit 1; PFAM: Glycine cleavage system P-protein-like; PRIAM: Glycine dehydrogenase (decarboxylating); SPTR: Probable glycine dehydrogenase [decarboxylating] subunit 1; PFAM: Glycine cleavage system P-protein.
     
 0.776
ADW18866.1
Glycine dehydrogenase (decarboxylating) beta subunit; COGs: COG1003 Glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; InterPro IPR020580; KEGG: dps:DP0298 glycine dehydrogenase subunit 2; PFAM: Glycine cleavage system P-protein-like; SPTR: Probable glycine dehydrogenase, subunit 2; PFAM: Glycine cleavage system P-protein.
     
 0.775
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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