STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
tpxThiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (166 aa)    
Predicted Functional Partners:
ADW17909.1
COGs: COG0605 Superoxide dismutase; InterPro IPR019831: IPR019832: IPR001189: IPR019833; KEGG: efa:EF0463 superoxide dismutase, Mn; PFAM: Manganese/iron superoxide dismutase-like; PRIAM: Superoxide dismutase; SPTR: Superoxide dismutase; PFAM: Iron/manganese superoxide dismutases, alpha-hairpin domain; Iron/manganese superoxide dismutases, C-terminal domain.
  
  
 0.882
ADW18656.1
Intracellular protease, PfpI family; COGs: COG0693 Putative intracellular protease/amidase; InterPro IPR006286: IPR002818; KEGG: rrs:RoseRS_1742 PfpI family intracellular peptidase; PFAM: ThiJ/PfpI domain-containing protein; SPTR: Intracellular protease, PfpI family; TIGRFAM: intracellular protease, PfpI family; PFAM: DJ-1/PfpI family; TIGRFAM: intracellular protease, PfpI family.
  
 
 0.706
fliN
COGs: COG1886 Flagellar motor switch/type III secretory pathway protein; InterPro IPR001172: IPR001543: IPR012826; KEGG: dps:DP2669 flagellar motor switch protein (FliN); PFAM: surface presentation of antigens (SPOA) protein; SPTR: Probable flagellar motor switch protein (FliN); TIGRFAM: flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); TIGRFAM: flagellar motor switch protein FliN.
    
   0.676
ADW18872.1
Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: ppd:Ppro_1966 ferric uptake regulator family protein; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family.
  
  
 0.606
ADW19439.1
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COGs: COG0450 Peroxiredoxin; InterPro IPR000866: IPR019479: IPR017936; KEGG: gsu:GSU3246 thioredoxin peroxidase; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like; SPTR: Thioredoxin peroxidase; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family.
  
  
 0.606
ADW19141.1
Short-chain dehydrogenase/reductase SDR; COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002198: IPR002347; KEGG: dvl:Dvul_1374 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Oxidoreductase, short-chain dehydrogenase/reductase family; PFAM: short chain dehydrogenase.
   
    0.605
ADW18973.1
COGs: COG0851 Septum formation topological specificity factor; InterPro IPR005527; KEGG: maq:Maqu_2337 cell division topological specificity factor MinE; PFAM: Septum formation topological specificity factor MinE; SPTR: Cell division topological specificity factor; TIGRFAM: cell division topological specificity factor MinE; PFAM: Septum formation topological specificity factor MinE; TIGRFAM: cell division topological specificity factor MinE.
   
    0.602
ADW18868.1
COGs: COG0509 Glycine cleavage system H protein (lipoate-binding); InterPro IPR002930: IPR017453: IPR003016; KEGG: dps:DP0300 glycine cleavage system, H protein; PFAM: glycine cleavage H-protein; SPTR: Glycine cleavage system H protein; TIGRFAM: glycine cleavage system H protein; PFAM: Glycine cleavage H-protein; TIGRFAM: glycine cleavage system H protein.
  
    0.583
ADW19311.1
Cysteine synthase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR001926: IPR015803: IPR015273: IPR005856: IPR 002308: IPR001216; KEGG: dal:Dalk_3820 cysteine synthase; PFAM: Cysteinyl-tRNA synthetase class Ia; Pyridoxal-5'-phosphate-dependent protein beta subunit; Cysteinyl-tRNA synthetase class Ia DALR; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase; cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthases; cysteinyl-tRNA synthetase; cysteine synthase B.
  
  
 0.571
ADW16844.1
Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: dps:DP2966 iron-dependent repressor; PFAM: iron dependent repressor; SMART: iron dependent repressor; SPTR: Probable iron-dependent repressor; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain.
  
  
 0.514
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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