STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18872.1Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: ppd:Ppro_1966 ferric uptake regulator family protein; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family. (161 aa)    
Predicted Functional Partners:
ADW19439.1
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COGs: COG0450 Peroxiredoxin; InterPro IPR000866: IPR019479: IPR017936; KEGG: gsu:GSU3246 thioredoxin peroxidase; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like; SPTR: Thioredoxin peroxidase; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family.
  
  
 0.738
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.706
tpx
Thiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
  
  
 0.606
ADW19090.1
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR017936: IPR013766: IPR006662: IPR017937: IPR 005746; KEGG: dak:DaAHT2_1638 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
  
 
 0.527
ADW16435.1
Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: paa:Paes_2294 ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family.
  
     0.518
ADW17621.1
Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: dak:DaAHT2_0358 iron (metal) dependent repressor, DtxR family; PFAM: iron dependent repressor; SMART: iron dependent repressor; SPTR: Iron (Metal) dependent repressor, DtxR family; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain.
  
  
 0.518
ADW17962.1
COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284: IPR007627: IPR007630: IPR000943: IPR 016263; KEGG: dps:DP2192 RNA polymerase sigma-B factor; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; alternative sigma factor RpoH.
  
 
 0.501
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.490
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.488
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.483
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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