STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18876.1COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR004586: IPR014016: IPR014017: IPR000212; KEGG: gme:Gmet_1893 DNA helicase/exodeoxyribonuclease V subunit beta; PFAM: UvrD/REP helicase; PRIAM: Exodeoxyribonuclease V; SPTR: DNA helicase/exodeoxyribonuclease V, beta subunit; TIGRFAM: exodeoxyribonuclease V, beta subunit; PFAM: UvrD/REP helicase; TIGRFAM: exodeoxyribonuclease V, beta subunit. (1172 aa)    
Predicted Functional Partners:
ADW18875.1
COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR006344; KEGG: pct:PC1_0915 exonuclease V subunit alpha; PRIAM: Exodeoxyribonuclease V; SPTR: Exodeoxyribonuclease V, alpha subunit; TIGRFAM: exodeoxyribonuclease V, alpha subunit; PFAM: Putative ATPase (DUF699); Viral (Superfamily 1) RNA helicase; TIGRFAM: exodeoxyribonuclease V, alpha subunit.
 
 0.998
ADW18877.1
COGs: COG1330 Exonuclease V gamma subunit; InterPro IPR006697; KEGG: gur:Gura_0582 exodeoxyribonuclease V, gamma subunit; PRIAM: Exodeoxyribonuclease V; SPTR: DNA helicase/exodeoxyribonuclease V, gamma subunit; TIGRFAM: exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V, gamma subunit; TIGRFAM: exodeoxyribonuclease V, gamma subunit.
 
 0.998
ADW16641.1
Helicase, RecD/TraA family; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR006345; KEGG: dat:HRM2_23450 RecD1; SPTR: RecD1; TIGRFAM: helicase, RecD/TraA family; PFAM: Viral (Superfamily 1) RNA helicase; TIGRFAM: helicase, putative, RecD/TraA family.
 
 0.951
ADW17332.1
HRDC domain protein; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR002121; KEGG: dat:HRM2_02150 helicase-family protein; PFAM: HRDC domain protein; SMART: HRDC domain protein; SPTR: Helicase-family protein; PFAM: PIF1 helicase; HRDC domain.
  
 
 0.874
ADW16923.1
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...]
     
 0.650
ADW18878.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR000014: IPR001610: IPR003661: IPR 003594: IPR001789: IPR005467: IPR000700: IPR013656: IPR013767; KEGG: sfu:Sfum_2401 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response [...]
       0.546
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.528
ADW18546.1
COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR003141: IPR004013: IPR011708: IPR004365: IPR 004805; KEGG: dps:DP1663 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: Related to DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc).
  
  
 0.522
ADW18759.1
COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); InterProIPR001679: IPR013840: IPR003583: IPR001357: IPR 018239: IPR013839: IPR004150: IPR004149: IPR000445; KEGG: dak:DaAHT2_2447 DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase adenylation; NAD-dependent DNA ligase OB-fold; helix-hairpin-helix motif; BRCT domain protein; PRIAM: DNA ligase (NAD(+)); SMART: NAD-dependent DNA ligase; Helix-hairpin-helix DNA-binding class 1; BRCT domain protein; SPTR: DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase OB-fold domain; [...]
  
 
 0.504
ADW19358.1
SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR003395; KEGG: ppd:Ppro_2570 SMC domain-containing protein; PFAM: SMC domain protein; SPTR: SMC domain protein; TIGRFAM: exonuclease SbcC.
 
  
 0.495
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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