Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ADW18876.1COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR004586: IPR014016: IPR014017: IPR000212; KEGG: gme:Gmet_1893 DNA helicase/exodeoxyribonuclease V subunit beta; PFAM: UvrD/REP helicase; PRIAM: Exodeoxyribonuclease V; SPTR: DNA helicase/exodeoxyribonuclease V, beta subunit; TIGRFAM: exodeoxyribonuclease V, beta subunit; PFAM: UvrD/REP helicase; TIGRFAM: exodeoxyribonuclease V, beta subunit. (1172 aa)    
Predicted Functional Partners:
ADW18875.1
COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR006344; KEGG: pct:PC1_0915 exonuclease V subunit alpha; PRIAM: Exodeoxyribonuclease V; SPTR: Exodeoxyribonuclease V, alpha subunit; TIGRFAM: exodeoxyribonuclease V, alpha subunit; PFAM: Putative ATPase (DUF699); Viral (Superfamily 1) RNA helicase; TIGRFAM: exodeoxyribonuclease V, alpha subunit.
 0.998
ADW18877.1
COGs: COG1330 Exonuclease V gamma subunit; InterPro IPR006697; KEGG: gur:Gura_0582 exodeoxyribonuclease V, gamma subunit; PRIAM: Exodeoxyribonuclease V; SPTR: DNA helicase/exodeoxyribonuclease V, gamma subunit; TIGRFAM: exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V, gamma subunit; TIGRFAM: exodeoxyribonuclease V, gamma subunit.
 0.998
ADW16641.1
Helicase, RecD/TraA family; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR006345; KEGG: dat:HRM2_23450 RecD1; SPTR: RecD1; TIGRFAM: helicase, RecD/TraA family; PFAM: Viral (Superfamily 1) RNA helicase; TIGRFAM: helicase, putative, RecD/TraA family.
 
 0.964
ADW17332.1
HRDC domain protein; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR002121; KEGG: dat:HRM2_02150 helicase-family protein; PFAM: HRDC domain protein; SMART: HRDC domain protein; SPTR: Helicase-family protein; PFAM: PIF1 helicase; HRDC domain.
  
 
 0.884
ADW16923.1
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...]
     
 0.595
ADW18775.1
Exodeoxyribonuclease III Xth; COGs: COG0708 Exonuclease III; InterProIPR003265: IPR000097: IPR004808: IPR020847: IPR 020848: IPR004036: IPR003651: IPR005135; KEGG: dak:DaAHT2_1503 exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; HhH-GPD family protein; iron-sulfur cluster loop; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD family protein; SPTR: Exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; HhH-GPD superfamily base excision DNA repair protein; H [...]
     
 0.576
ADW18546.1
COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR003141: IPR004013: IPR011708: IPR004365: IPR 004805; KEGG: dps:DP1663 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: Related to DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc).
  
  
 0.541
ADW17589.1
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532: IPR002547: IPR005121: IPR005146: IPR 005147; KEGG: dps:DP1423 phenylalanyl-tRNA synthetase, beta chain; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase beta chain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bac [...]
     
 0.536
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.530
ADW19358.1
SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR003395; KEGG: ppd:Ppro_2570 SMC domain-containing protein; PFAM: SMC domain protein; SPTR: SMC domain protein; TIGRFAM: exonuclease SbcC.
 
  
 0.523
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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